| 藏红花对酒精及酒精加四氯化碳所致大鼠肝损伤的防治作用 |
| |
| 引用本文： | 马安林,吴铁墉,董恩玉,李红. 藏红花对酒精及酒精加四氯化碳所致大鼠肝损伤的防治作用[J]. 中西医结合肝病杂志, 2000, 10(6): 34-35 |
| |
| 作者姓名： | 马安林 吴铁墉 董恩玉 李红 |
| |
| 作者单位： | 中日友好医院,北京,100029 |
| |
| 摘 要： | 目的：探索藏红花对酒精及酒精四氯化碳所致大鼠肝损伤的防治作用。方法：取Wistar雄性大鼠设5组，分别灌胃生理盐水（A）、白酒（B）、白酒加藏红花（C），白酒加CCl4(D),在D组基础上加用藏红花（E）对5组大鼠血清ALT和肝脏组织学病变进行比较。结果：藏红花能降低白酒和四氯化碳引起的ALT升高（P＜0．05）；B、C组及D、E组互比肝脏组织学改变有明显差异（P＜0．05）。结论：藏红花对酒精及酒精四氯化碳所致肝损伤有一定的防治作用。
|
| 关 键 词： | 藏红花 氨酸转氨酶 酒精性肝损伤 大鼠 防治 |
| 修稿时间： | 2000-04-09 |
Prevention and Treatment of Saffron on Experimental Alcoholic and CCl4 Liver Injury in Wistar Rats |
| |
| Ma Anlin,Wu Tieyong,Dong Enyu,et al.. Prevention and Treatment of Saffron on Experimental Alcoholic and CCl4 Liver Injury in Wistar Rats[J]. Chinese Journal of Integrated Traditonal and Western Medicine on Liver Diseases, 2000, 10(6): 34-35 |
| |
| Authors: | Ma Anlin Wu Tieyong Dong Enyu et al. |
| |
| Abstract: | To explore saffron in the treatment of alcohol and CCl4 induced liver injury in the rat. Methods:Fivegroups (ten rats/group) of male wistar rats were studied. Rats in group A were fed 0. 9% NaCl continuously for up to 8 weeks via intragastric feeding; Rats in group B and C were fed ethanol (9-11g/kg/d) continuously for up to 8 weeks via intragastric feeding. At the same time rats in C group were added saffron: Rats in group D and E were fed ethanol for 4 weeks, then being exposed to CCl4 (0. 0125ml/100g, 3 times/week) for 4 weeks,Rats in group E were given saffron too. ALT and liver specimens was measured and evaluted. Results; Serum level of ALT decreased significantly (P< 0. 05) in saffron rats as compared with alcoholic and CCl4 rats.Liglt microscopic examination showed that Saffron groups have abvious pathological changes. Conclusion: Saffron may be therapeutically useful and prevention in the alcohol and CCl4 hepatic injury in rats. |
| |
| Keywords: | Saffron ALT Alcoholic Liver Injury Rat |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
