Basal metabolic rate in healthy Down's syndrome adults |
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Authors: | M. B. SCHAPIRO S. I. RAPOPORT |
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Affiliation: | Laboratory of Neurosciences, Section on Brain Aging and Dementia, National Institute on Aging, Clinical Center, Bcthesda, Maryland, USA |
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Abstract: | ABSTRACT. Basal metabolic rale (BMR) was measured on 2 consecutive Jays with an open-circuit, indirect calorimeter in 16 healthy subjects with trisomy 21 Down's syndrome (DS) aged 22-35 years and 11 healthy control volunteers aged 20-31 years. BMR measurements Jut mil differ on consecutive days in either the DS or control groups. Absolute BMR, BMR corrected for surface area, and HMR corrected tor lean body mass did not differ between the DS subjects and the volunteers. The per cent of predicted BMR also did not Jitter between the two groups. These results suggest that systems controlling basal metabolism are not affected by extra gcnomic material from chromosome 21. |
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