Effect of surgical treatment on stage IV melanoma |
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| Authors: | M A Hena L J Emrich R N Nambisan C P Karakousis |
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| Affiliation: | 1. Aga Health Insurance Hospital, Dakahlia, Egypt;2. Department of Analytical Chemistry, Faculty of Pharmacy, Zagazig University, Egypt;1. Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada;2. Department of Epidemiology and Biostatistics, McGill University, Montréal, Québec, Canada;1. Department of Molecular Pharmacology, Institute of Biomedical Sciences, Tokushima University Graduate School, 1-78-1 Sho-machi, Tokushima 770-8505, Japan;2. School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata 700032, India;3. Department of Otolaryngology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima 770-8503, Japan;4. Department of Parmacognosy, Institute of Biomedical Sciences, Tokushima University Graduate School, 1-78-1 Sho-machi, Tokushima 770-8505, Japan;5. Department of Pharmaceutical Chemistry, Institute of Biomedical Sciences, Tokushima University Graduate School, 1-78-1 Sho-machi, Tokushima 770-8505, Japan;6. Department of Molecular Studies for Incurable Diseases, Institute of Biomedical Sciences, Tokushima University Graduate School, Fujii Memorial Institute of Medical Sciences, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan |
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| Abstract: | One hundred eighty patients with hematogenous metastases from malignant melanoma were reviewed. Complete resection of the gross tumor was technically feasible in 33 percent of the cases. Patients who had complete resection of the gross tumor had an estimated median survival time of 11.4 months and an estimated 5 year survival rate of 14 percent. Patients with solitary lesions removed had a median survival time of 22.8 months and a 5 year survival rate of 23 percent. Patients with distant subcutaneous metastases completely removed had a median survival time of 31.9 months and a 5 year survival rate of 29 percent. Surgical resection of distant metastases, when technically feasible, particularly for solitary lesions and subcutaneous locations, increases the length of survival of patients with disseminated melanoma. |
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