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Surgical Treatment of Carcinoma of Esophagus and Gastric Cardia—A 34—year Investigation
引用本文:SHAOLingfang CHENYuhang 等.Surgical Treatment of Carcinoma of Esophagus and Gastric Cardia—A 34—year Investigation[J].中德临床肿瘤学杂志,2002,1(2):61-64.
作者姓名:SHAOLingfang  CHENYuhang
作者单位:DepartmentofThoraicSurgery,HencerCancerInstituteandHospital,Zhengzhou450003
摘    要:Methods The patients were divided into A,Band C groups:3155 patients (group A)were treated surgically in the first 14 years ,5952 patients (group B)in the next 10 years ,and 3863 patients (group C)in the last 10 years .The early stage lesions (Tis ,Ti)were as-signed as a separate group.The results of these groups were compared. Results The respectability for esophageal and gastric cardiac carcinoma wsa 94.0% and 84.4% respectively ,and the overall respectability .The overall operative mortality was 1.8%,it was 4.4% for group A, 1.6% for group B,and 0.5% for group C.The overall 5-year sur-vival was 31.6%.The 5-year survival for groups A, B,C and the early stage group was 27.0% ,29.1%,32.0% and 92.6%,respect-tively.Among the 3 temporal groups,differences were observed in tems of lesion stage,location and size,surgery with or without com-bined therapy and postoperative complications. Conclusion Best results were achieved in the early cases,with a respectability of 100% and a 5-year survival of 92.6%.The indications for surgical treatment were extended with increased respectability and decreased mortality.Subtotal esophagectomy combined with cervical esophagogastrostomy was advocated as the procedure of first choice for esophageal carcinoma in attempt to diminish the chance of recur-rence,and to achieve better outcomes by using combined therapy for patients with≥stage Ⅲ lesion.

关 键 词:食管癌  胃贲门癌  外科手术  治疗  调查统计  年代  存活率
收稿时间:20 June 2002

Surgical treatment of carcinoma of esophagus and gastric cardia—A 34-year investigation
Lingfang Shao,Yuhang Chen,Zhongren Gao,Gongquan Wei,Jinliang Xu,Minyao Chen,Jinghua Cheng.Surgical treatment of carcinoma of esophagus and gastric cardia—A 34-year investigation[J].The Chinese-German Journal of Clinical Oncology,2002,1(2):61-64.
Authors:Lingfang Shao  Yuhang Chen  Zhongren Gao  Gongquan Wei  Jinliang Xu  Minyao Chen  Jinghua Cheng
Institution:(1) Department of Thoracic Surgery, Henan Cancer Institute and Hospital, 450003 Zhengzhou, China
Abstract:Objective To understand the progress in surgical treatment of 12 970 patients with carcinoma of esophagus and gastric cardiac during 1965–1998. Methods The patients were divided into A, B and C groups: 3 155 patients (group A) were treated surgically in the first 14 years, 5 952 patients (group B) in the next 10 years, and 3 863 patients (group C) in the last 10 years. The early stage lesions (Tis, T1) were assigned as a separate group. The results of these groups were compared. Results The resectability for esophageal and gastric cardiac carcinoma was 94.0% and 84.4% respectively, and the overall resectability was 91.3%. The resectability for groups A, B, C and the early stage group was 82.1%, 85.1%, 90.2% and 100%, respectively. The overall operative mortality was 1.8%, it was 4.4% for group A, 1.6% for group B, and 0.5% for group C. The overall 5-year survival was 31.6%. The 5-year survival for groups A, B, C and the early stage group was 27.0%, 29.1%, 32.0% and 92.6%, respectively. Among the 3 temporal groups, differences were observed in terms of lesion stage, location and size, surgery with or without combined therapy and postoperative complications. Conclusion Best results were achieved in the early cases, with a resectability of 100% and a 5-year survival of 92.6%. The indications for surgical treatment were extended with increased resectability and decreased mortality. Subtotal esophagectomy combined with cervical esophagogastrostomy was advocated as the procedure of first choice for esophageal carcinoma in attempt to diminish the chance of recurrence, and to achieve better outcomes by using combined therapy for patients with≥stage III lesion.
Keywords:esophageal neoplasms  gastric cardiac neoplasms  surgical procedures  operative  survival rate  prognosis
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