手足口病患儿联合检测肌酸激酶同工酶MB、心肌肌钙蛋白Ⅰ在合并病毒性心肌炎诊断中的价值

目的探讨手足口病患儿联合检测血清中肌酸激酶同工酶MB（CK—MB）、心肌肌钙蛋白Ⅰ（cTnI）水平对诊断合并病毒性心肌炎的价值。方法将188倒HFMD患儿分为确诊合并精毒性心肌炎组、疑似舍并病毒性心肌炎组、无合并病毒性心肌灸组。所有惠儿清晨空腹采集静脉血，检测血清中的肌酸激酶同工酶MB（CK—MB）、心肌肌钙蛋白Ⅰ（cTnI）水平，对结果进行统计分析。结果确诊合并病毒性心肌炎组与疑似合并病毒性心肌炎组血清中CK—MB、cTnI均高于无合并病毒性心肌炎组，差异有统计学意义（P〈0．05）；确诊合并病毒性心肌炎组血清中CK—MB、cTnI与疑似合并病毒性心肌炎组比较差异无统计学意义（P〉0．05）。确诊组与疑似组两项检测中的总异常率均分别高于两纽中CK—MB、cTnI单独检测异常率（P〈0．05，P〈0．05）。结论CK—MB、cTnI在HFMD中诊断合并病毒性心肌炎有重要意义；HFMD患儿同时检测血清中CK—MB、cTrI水平，可以提高合并病毒性心肌炎的捡出率。

The value of combining detecting creatine kinase isoenzyme MB and cardiac troponin I for diagnosis of viral myocarditis in hand-foot-mouth disease patients

Objective To explore the role of combined detection of serum of patients of hand, foot and mouth disease of creafine kinase isoenzyme MB （CK-MB）, cardiac troponin Ⅰ（cTnI） levels in the diagnosis of viral myocarditis in the combined clinical significance. Meth-ods Divide 188 patients of HFMD into viral myocardifis confirmed the group of incorporate with viral myocarditis, group of suspected incorporate with viral myocarditis, group of without incorporate with viral myocarditis. All children with fasting blood collection, testing of serum creafine kinase isoenzyme MB （CK-MB）, cardiac troponin Ⅰ （cTnI） level of statistical analysis of the results. Results Results of group of incorporate with viral myocarditis and group of suspected incorporate with viral myocarditis in serum CK - MB, eTnl were higher than group of without in- corporate with of viral myocarditis without exception, the difference was significant in statistics （P 〉 0.05） ; There was no significant difference between group of incorporate with viral myocarditis CK - MB, cTnI and group of suspected incorporate with viral myocarditis in serum （ P 〈 0. 05）. The total detection rate of abnormalities of CK - MB, cTnI in group of incorporate with viral myocarditis and group of suspected incorpo- rate with viral myoearditis was higher than separate rate of detection of abnormalities CK - MB or eTnl （P 〈 0.05, P 〈 0. 05 ）. Conclusion CK - MB and cTnI have importance significance in the diagnosis of HFMD incorporate with viral myocarditis. Patients of HFMD jerque CK - MB, cTnI levels in serum at the same time can improve the rate of discovering incorporate with viral myocarditis.