全数字化乳腺摄影及定位活组织检查在触诊阴性乳腺癌诊断中的应用

目的探讨全数字化乳腺摄影（FFDM）及定位活组织检查在触诊阴性乳腺癌诊断中的应用价值。方法回顾性分析42例临床触诊阴性，乳腺常规摄片提示有可疑乳腺癌征象，行定位活组织检查后经病理证实的乳腺癌病例的影像学表现。结果42例中，5例显示微小结节，8例显示局限性致密浸润，11例显示结构紊乱，18例显示微小钙化。病理类型为导管内癌23例，小叶原位癌2例，导管内癌伴早期浸润12例，浸润性导管癌3例，乳头状瘤癌变2例。全部病例均在定位导丝指引下行病灶切除，切除标本摄片确认属目标病灶。结论FFDM能清晰显示乳腺癌的直接和间接征象，结合定位活组织检查对临床触诊阴性乳腺癌的诊断具有重要价值。

Utility of full-field digital mammography and localization in breast biopsy in diagnosis of nonpalpable breast cancer

Objective To investigate the utility of full-field digital mammography (FFDM) and localization and biopsy in diagnosis of nonpalpable breast cancer. Methods 42 cases with suspect breast cancer by routine film reading but negative clinical palpation were performed localization and biopsy under X-ray orientation and diagnosed with breast cancer by pathology. The characters of those cases were studied.Results Among 42 cases, 5 cases showed micronodules, 8 cases demonstrated local dense infiltration, 11cases had architecture distortion, 18 cases demonstrated micro-calcifications. The type of pathology comprised of intraductal carcinoma (23 cases), tabular carcinoma in situ (2 cases), early infiltration of ductal carcinoma (12 cases), infiltrating ductal carcinoma (3 cases), papilloma carcinoma (2 cases). Conclusion FFDM can clearly show direct and indirect X-ray signs of breast cancer, combined with localization and biopsy the nonpalpable breast cancer can be easily diagnosed.