臭氧关节腔内注射联合中药“威灵仙”熏洗治疗膝骨性关节炎疗效观察

目的：探讨臭氧关节腔内注射联合中药＂威灵仙＂熏洗治疗膝骨性关节炎的疗效。方法：2009年10月—2010年10月,采用臭氧关节腔内注射联合中药＂威灵仙＂熏洗治疗膝骨性关节炎患者120例151膝,男47例,女73例,年龄51～82岁,平均64.1岁,均经影像学及临床诊断为膝骨性关节炎。随机分为3个治疗组,分别采用关节腔注入浓度为35μg/mL的医用臭氧和中药＂威灵仙＂洗剂熏洗以及二者联合治疗。结果：所有患者分别于治疗后1、3、6个月时进行随访,采用视觉模拟疼痛评分（VAS）以及HSS膝关节功能评分法,各组患者膝关节疼痛程度在各个随访时间点均较术前明显改善,C治疗组在各随访时间点疼痛及膝关节功能改善均较A、B治疗组明显并有统计学差异,显示了较其余两组优越的治疗效果。无任何与治疗相关的并发症发生。结论：臭氧关节腔内注射联合中药＂威灵仙＂熏洗治疗膝骨性关节炎是一种安全、有效的方法,其疗效优于以上疗法的单独使用。

Therapeutic Effect of Medical Ozone Combined with Weilinxian on Knee Osteoarthritis

Objective ： To observe the therapeutic effect of the treatment for knee osteoarthritis （ KOA ） using injection of medical ozone combined with washing of Weilinxian. Methods ： From October 2009 to October 2010,120 patients with KOA were treated by the injection with ozone （ concentration of 35 p~ g/mL ） and washing with Weilinxian. 47 males and 73 females with average age of 64.1 were included. The patients were randomly divided into 3 groups, group A accepted injection of ozone, group B accepted washing of Weilinxian and group C accepted the combined treatment of ozone and Weilinxian. Results ： All patients were followed at 1,3 and 6 months after treatment. The VAS and HSS scores were used to evaluate the clinical effects. Satisfied effects were found in each group, but the effect of ozone injection combined with washing of Weilinxian was significantly better than using ozone or Weilinxian alone. No complications related to the treatment occurred. Conclusions ： Injection of medical ozone combined with washing of Weilinxian is a safe and effective method for knee osteoarthritis.