| 一步法检测AFB和斑点法检测LAM-IgG诊断结核性脑膜炎 |
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| 引用本文： | 王传生,薛承岩,刘霞.一步法检测AFB和斑点法检测LAM-IgG诊断结核性脑膜炎[J].承德医学院学报,2003,20(1):11-13. |
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| 作者姓名： | 王传生 薛承岩 刘霞 |
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| 作者单位： | 1. 承德市卫生学校,河北,承德,067000
2. 承德医学院附属医院 |
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| 摘 要： | 目的 :评估联合应用一步法检测抗酸杆菌 (AFB)和斑点法检测抗阿拉伯糖甘露糖脂 Ig G抗体(L AM- Ig G)方法诊断结核性脑膜炎 (结脑 )的价值。方法 :结脑患者为实验组 ,采集脑脊液本本 (CSF)为标本 ,应用一步法检测 AFB、斑点法检测 LAB- Ig G。结果 :实验组 ,一步法检测 AFB阳性率为 6 7.4 %(6 2 /92 )、斑点法检测 LAM- Ig G阳性率为 5 7.6 % (5 3/92 )、两者联检的阳性率为 71.7% (6 6 /92 ) ,较常规方法的阳性率有显著性提高 (ρ<0 .0 0 1)。结论 :对 CSF标本联合应用一步法检测 AFB和斑点法检测LAM- Ig G,在诊断结脑方面有较高的应用价值
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| 关 键 词： | 脑脊液 抗酸杆菌 一步法 抗阿拉伯糖甘露糖脂IgG抗体 斑点法 诊断 结核性脑膜炎 |
| 文章编号： | 1004-6879(2003)01-0011-03 |
| 修稿时间： | 2002年5月10日 |
COMBINED DETECTION OF AFB AND LAM-IgG BY"SINGLE STEP AFB DETECTION" AND "DOT IGFA" IN CSF FOR DIAGNOSIS OF TUBERCULOUS MENINGITIS |
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| WANG Chuan sheng,XUE Cheng yan,LIU Xia.COMBINED DETECTION OF AFB AND LAM-IgG BY"SINGLE STEP AFB DETECTION" AND "DOT IGFA" IN CSF FOR DIAGNOSIS OF TUBERCULOUS MENINGITIS[J].Journal of Chengde Medical College,2003,20(1):11-13. |
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| Authors: | WANG Chuan sheng XUE Cheng yan LIU Xia |
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| Abstract: | Objctive:To appraise the value on combined detection of acid fast bacilli(AFB)and Lipoarabionomannan G antibody(LAM IgG) in cerebrospinal fluid(CSF)for diagnosis of tuberculous meningitis.Methods:The test group was the patients with tuberculous meningitis.AFB was detected in CSF with"single step AFB detection"and LAM IgG was detected in CSF with"dot IGFA".Results:The positive rate of AFB was 67.4%(62/92)and LAM IgG was 57.6%(53/92) and AFB+LAM IgG was 71.7%(66/92) in tuberculous meningitis group.Conclusion:AFB and LAM IgG are useful index to diagnose tuberculous meningitis.Combined using of them can improve the sensitivity. |
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| Keywords: | Cerebrospinal fluid Acid fast bacillus/single step AFB detection Lipoarabinomannan G antibody/dot immunogold filtration assay Diagnosis Tuberculous meningitis |
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