| 唾液腺提取物抗衰老作用初步研究 |
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| 引用本文： | 程光宇,唐梓进,吴京燕,毛伟平,杨佐宪. 唾液腺提取物抗衰老作用初步研究[J]. 中国老年学杂志, 2003, 23(2): 119-120 |
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| 作者姓名： | 程光宇 唐梓进 吴京燕 毛伟平 杨佐宪 |
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| 作者单位： | 南京师范大学生命科学学院,江苏,210097 |
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| 基金项目： | 江苏省“九五”科技攻关项目 (BE960 4 8) |
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| 摘 要： | 目的：研究唾液腺提取物（SGE）的抗衰老作用。方法：以400mg/kg和1500mg/kg剂量的SGE分别饲喂SD大鼠75d，以400mg/kg剂量的SGE饲喂HIN小鼠45d，采用NBT光化还原法和TBA荧光法分别测定其红细胞SOD活性及血清LPO含量，同时测定胸腺和脾指数。结果：SGE均能显著提高大、小鼠血细胞SOD活性和大鼠SOD比活性，显著降低大、小鼠血清LPO含量，提高大鼠胸腺指数，结论：SGE能显著提高动物红细胞SOD活性，降低血清LPO含量，提高胸腺指数，具有明显的抗衰老作用。
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| 关 键 词： | 唾液腺提取物 抗衰老作用 超氧化物歧化酶 过氧化脂质 |
| 文章编号： | 1005-9202(2003)02-0119-02 |
| 修稿时间： | 2002-08-07 |
The studies on antiaging actions of salivary gland extract (SGE) |
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| CHENG Guang yu,TANG Zhi jin,WU Jing yan,et al. The studies on antiaging actions of salivary gland extract (SGE)[J]. Chinese Journal of Gerontology, 2003, 23(2): 119-120 |
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| Authors: | CHENG Guang yu TANG Zhi jin WU Jing yan et al |
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| Abstract: | Objective To investigate the effect of SGE on antiaging actions. Methods 400 and 1500 mg/kg of SGE were given to SD rats everyday for 75 days, respectively, and 400 mg/kg of SGE was given to NIH mice everyday for 45 days, the SOD activity in red cell and the LPO content in serum were determined by NBT, TBA test methods, and the thymus and spleen index were also examined.Results Compare with the control group, SGE could increase significantly the SOD activity in red cell and could decrease significantly the content of LPO in serum, it also could raise the thymus index of SD rats.Conclusions SGE can increase the SOD activity and thymus index , and decrease the LPO content in animals, it has the antiaging actions. |
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| Keywords: | Salivary gland extract Antiaging SOD LPO |
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