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Ex vivo Inhibition of NF-κB Signaling in Alloreactive T-cells Prevents Graft-Versus-Host Disease |
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| Authors: | M. J. O'Shaughnessy C. Vogtenhuber K. Sun R. Sitcheran A. S. Baldwin W. J. Murphy L. Dang B. Jaffee E. Palmer J. S. Serody B. R. Blazar |
| Affiliation: | Department of Pediatrics, Division of Bone Marrow Transplantation, University of Minnesota Cancer Center, Minneapolis, MN;Department of Microbiology and Immunology, University of Nevada, Reno, NV;University of North Carolina-Chapel Hill, Lineberger Cancer Center, Chapel Hill, NC;Millennium Pharmaceuticals, Cambridge, MA;Department of Research, Laboratory of Transplantation Immunology and Nephrology, University Hospital-Basel, CH-4031 Basel, Switzerland |
| Abstract: | |
| Keywords: | Alloantigens allogeneic allograft tolreance alloreactive T cells allorecognition allotransplantation bone marrow transplantation CD4+ T cells donor T-cell graft-versus-host disease immune tolerance nuclear factor—kappa B (NF-κB) T cell T-cell signaling transplantation tolerance |