深低温冷冻同种异体骨在下颌骨大块缺损修复中的应用

目的探讨深低温冷冻(深冻)同种异体下颌骨移植的临床方法和应用价值。方法采用深冻同种异体下颌骨修复10例下颌骨大块缺损的病例,术中尽可能保留受植床的骨膜,异体骨浸泡生理盐水加抗生素30min,并在植骨块与受植骨块之间嵌入医用诱导骨基质,严密缝合口腔黏膜,口外放置持续负压引流。结果本组10例患者术后随访1~3年,X线片见患者下颌骨与移植骨生长愈合良好,未出现明显的高度降低。结论深冻辐射同种异体下颌骨用于下颌骨大块缺损的修复,可减少患者因取骨增加的痛苦,缩短手术时间,减少手术痛苦,在临床上是较佳的选择。

Application of allogenic mandibular transplantion irradiated at profound hypothermia in repair of mandibular defection

Objective To explore the clinical application of the allogenic mandibular tansplantation,which was irradiated with profound hypothermia and to estimated its value.Methods In 10 cases of severe defections of most part of the mandible,the method repairing them by the allogenic tansplantation was adopted at the profound hypothermia.During the operation,we saved the periosteum of the recipient bed as possible as we could.The allogenic bone was soaked in the physiologic saline with antibiotic for 30 min.Moreover,the medical revulsant matrix was inserted between the bone graft and recipient bone,finally,sewing up the oral mucosa rigorously.After the operation,the negative pressure drainage was given persistently.Results All the patients included,accepted following-up visits for 1 to 3 years.According to the X-ray,the mandible and the transplantion grew very well,without obvious descent in height.Conclusion Allogenic mandibular transplantion irradiated at the profound hypothermia can be used in the repair of the defection of major part of mandible.