老年支气管扩张合并感染的常见病原菌及其耐药性调查

目的调查分析老年支气管扩张合并感染的常见病原菌及其耐药情况,为临床合理应用抗菌药物提供依据。方法对189例老年支气管扩张合并感染的住院患者的痰培养和药敏结果进行回顾性调查分析。结果 189例患者病原菌检测阳性122例,阳性率为64.6%,病原菌以革兰阴性杆菌为和真菌为主,分别占59.5%和10.8%;主要致病的革兰阴性杆菌对头孢呋辛、氨苄西林等药物耐药率高,对β-内酰胺类、碳青酶烯类、氨基糖甙类和喹诺酮类药物的耐药率相对较低。结论老年支气管扩张合并感染病原菌以革兰阴性杆菌和真菌为主要条件致病菌,主要致病菌耐药率高,建议在药敏指导下用药。在未取得细菌药敏结果前可根据其病原菌分布特点经验性选择抗生素,宜采用联合抗菌药物治疗。

Investigation of common pathogenic bacteria and drug resistance in gerontism with bronchiectasis concurrent infection

Objective To investigate common pathogenic bacteria and drug resistance in gerontism with bronchiectasis concurrent infection,to make reasonable use of antibacterials.Methods Retrospectively analyzed sputum culture and drug sensitivity of 189 old patients with bronchiectasis concurrent infection.Results 122 people had masculine pathogenic bacteria,the masculine rate was 64.6%,then the rate of gram negative bacilli(GNB) was 59.5%,fungus was 10.8%;the drug resistance rate of GNB to Cefuroxime and Ampicillin was high,but to β-lactam antibiotics,carbapenem antibiotics,aminoglycosides and quinolones was low.Conclusion The main pathogenic bacteria in gerontism with bronchiectasis concurrent infection was gram negative bacilli and fungus,the rate of drug resistance was high,used antibiotics on the basis of drug sensitivity,selected antibiotics on the basis of the disposition feature of pathogenic bacteria,there was the best to use combination antibacterial drug therapy.