99Tcm-MIBI门控心肌灌注断层显像与超声心动测定左室射血分数的对比研究

目的探讨GE VG/Hawkeye单光子发射断层扫描仪(SPECT)随机携带3种左室射血分数算法对静息态99Tcm-MIBI门控心肌断层显像测定左室射血分数(LVEF)的临床应用价值。方法对103例、6组受检者进行门控心肌断层显像,使用3种算法分别测定3组左室射血分数(LVEF0、LVEF1、LVEF2),分别与M型超声心动获得的LVEF(UEF)进行对比分析。结果(1)103例受检者图像显影清晰;(2)根据不同算法获得门控心肌断层显像3组LVEF值(EF0、EF1、EF2)与超声心动图检查结果(UEF)均具有显著相关性(r0=0.948、r1=0.937、r2=0.940),其中EF0与UEF一致性较好;(3)静息态99Tcm-MIBI门控心肌断层显像测定左室射血分数可重复性好(P<0.05);(4)各组间t检验示:心肌缺血组、心梗组及扩张型心肌病组与正常组比较均存在显著性差异(P<0.05);高血压组、心肌炎组、扩张型心肌病和心肌缺血组比较均存在显著性差异(P<0.05);高血压组、心肌炎组、扩张型心肌病组与心梗组比较均存在显著性差异(P<0.05);扩张性心肌病组与心肌炎组比较亦存在显著性差异(P<0.05)。结论静息态99Tcm-MIBI静息态门控心肌断层显像测定左心室射血分数(LVEF)可靠,3种算法中以第一种最好,具有较好的临床应用价值。

Observations by 99Tcm-MIBI Gated SPECT Compared with Echocardiography on Left Ventricular Ejection Fraction

Objective To evaluate clinical value of 99Tcm-MIBI gated myocardial tomography imaging on left ventricular ejection fraction (LVEF) by three different algorithms of GE VG/Hawkeye SPECT.Methods Left ventricular ejection fraction by 99Tcm-MIBI gated SPECT were observed in 103 cases in 6 groups. Results (1)Left ventricular ejection fraction by rest 99Tc m-MIBI gated myocardial perfusions SPECT were successful in all 103 cases;(2)The correlation of LVEF between rest gated SPECT by three different algorithms and echocardiography were r0=0.948 (P<0.05) for gated SPECT EF0 and echocardiography, r1=0.937 (P<0.05) for gated SPECT EF1 and echocardiography, r2=0.941 (P<0.05) for gated SPECT EF3 and echocardiography, so the best correlation was obtained between gated SPECT EF0 and echocardiography ; ( 3 ) Reproducibility of LVEF from rest 99Tc m-MIBI gated myocardial perfusion SPECT was good(P<0.05);(4)In respectively LVEF, there was significant difference (P<0.05) between normal and ischemic group, myocardial infarction group, dilated myocardiopathy group(P<0.05). Conclusion LVEF can be reliable evaluated using rest 99Tc m-MIBI gated myocardial perfusion SPECT, in which the first algorithm was the best (LVEF0).