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某三甲医院2001至2009年抗-HIV阳性患者临床分析
引用本文:阮光萍,姚翔,潘兴华,庞荣清,蔡学敏,朱向情,邓永丽. 某三甲医院2001至2009年抗-HIV阳性患者临床分析[J]. 中华实验和临床感染病杂志(电子版), 2010, 4(4): 21-24. DOI: 10.3877/cma.j.issn.1674-1358.2010.04.006
作者姓名:阮光萍  姚翔  潘兴华  庞荣清  蔡学敏  朱向情  邓永丽
作者单位:解放军昆明总医院干细胞组织和器官工程研究中心,昆明市,650032
基金项目:云南省自然科学基金重点项目 
摘    要:目的分析某三甲医院2001至2009年门诊及住院患者HIV感染情况、感染率增长原因、感染途径,并提出相应的预防措施。方法采用ELISA检测抗-HIV,抗-HIV阳性者再用金标法检测,两种检测方法同为阳性者做确诊实验。金标法阴性者再用ELISA法双孔复查,双孔阴性报阴性结果,一阴一阳或双孔阳性同样做确诊实验。结果共检测109470例门诊和住院患者,其中HIV阳性患者354例,且呈逐年递增趋势,2001至2009年每年的HIV确诊阳性数差异具有统计学意义(F=9.23,P=0.000),传播途径以血液、性传播为主,大部分感染者具有不安全性行为、输血史、静脉吸毒史等。结论近年来HIV感染者逐渐增多,控制HIV传播的主要途径包括禁止不安全性行为、禁止吸毒、禁止输用未经标准检测的血液等。对高危人群和可能经医源性途径传播和感染HIV的患者进行常规抗-HIV检测是尽早发现HIV感染并防止其传播的必要措施;对AIDS患者及高危人群进行HIV感染特点及其传播方式的宣传教育。

关 键 词:抗-HIV  人类免疫缺陷病毒  确诊实验  初筛实验

Analysis on HIV antibody positive patients in certain hospital from 2001 to 2009
RUAN Guang-ping,YAO Xiang,PAN Xing-hua,PANG Rong-qing,CAI Xue-min,ZHU Xiang-qing,DENG Yong-li. Analysis on HIV antibody positive patients in certain hospital from 2001 to 2009[J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Version), 2010, 4(4): 21-24. DOI: 10.3877/cma.j.issn.1674-1358.2010.04.006
Authors:RUAN Guang-ping  YAO Xiang  PAN Xing-hua  PANG Rong-qing  CAI Xue-min  ZHU Xiang-qing  DENG Yong-li
Affiliation:.The Research Center of Stem Cell,Tissue and Organ Engineering,Kunming General Hospital of PLA,Kunming 650032,China
Abstract:Objective To analyze HIV infection condition,the causes and routes of infection of clinic service and inpatients in certain hospital from 2001 to 2009,and discuss the corresponding protective measures.Methods HIV antibodies were detected by ELISA method.The positive samples were detected by gold marked method.Positive samples tested by both methods were sent to final diagnosis.Negative samples detected by gold marked method were detected by ELISA diplopore detection.Diplopore negative samples were reported negative;one negative and one positive or two positive samples were sent to final diagnosis.Results Total of 109 470 clinic service and inpatients were detected,354 of whom were positive.The positive rate was increased year by year.The number of HIV positive diagnosis patients among years were significantly different(F = 9.23,P = 0.000).Major transmission routes were blood and sex.Most infected patients had unsafe sex,blood transfusion and intravenous drug taking.Conclusions HIV infected patients increased in recent years.Major ways to control HIV transmission include inhibition of unsafe sex,intravenous drug taking and transfusion of undetected blood.It is necessary to detect HIV antibody among high risk population and persons who may be infected by iatrogenic way,so that HIV infection may be found early and HIV transmission would be inhibited.HIV characteristics and modes of transmission should be taught to AIDS patients and high risk population.
Keywords:HIV antibody Human immunodeficiency virus Final diagnosis experiment Prescreening experiment
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