头孢西丁/头孢克肟序贯疗法治疗急性下呼吸道感染的临床研究

目的通过对头孢西丁序贯疗法及常规疗法治疗急性下呼吸道感染(ALRTI)的临床分析,探讨序贯疗法的可行性和优势所在,为临床合理应用抗生素提供依据。方法60例符合ALRTI诊断并达住院治疗标准的患者随机分为序贯疗法组(A组)和常规疗法组(B组),两组总疗程7～14d。同时统计比较两组的临床疗效,经济费用的差异。结果两组临床总有效率分别为80%和86.7%,两组结果比较差异无统计学意义(P>0.05)。A组人均总费用及抗菌药物费用明显低于B组(P<0.05)。结论头孢西丁与头孢克肟的序贯疗法治疗ALRTI可以保证临床疗效,并且可明显减轻患者经济负担。

Clinical Research about Sequential Therapy with Cefoxitin and Cefminox for Acute Lower Respiratory Tract Infection

Objective To discuss the efficacy and advantage about sequential therapy by analyzing ALRTI treated with sequential therapy with cefoxitin and cefminox as well as convential therapy respectively in order to provide reasonable reference for antibiotics application.Methods 60 patients in hospital with ALRTI were divided into two groups randomly,one group was treated with sequential therapy(group A),another was treated with general therapy(group B).The courses of treatment of the two groups were 7～14 days.The clinical efficacy and cost were compared.Results The total effective rates of the two groups were 80.0% and 86.7% respectively.There was no obvious significance between two groups(P>0.05).But group A had lower average total expenses and antibacterial drugs'expenses than group B.Conclusion The treatment efficacy of the sequential therapy with cefoxitin and cefminox for ALRTI was as the same as that of the general therapy with cefoxitin.Furthermore it can lighten patients' economic burden largely.