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不同加工方法对掌叶大黄中蒽醌类和酚酸类成分的影响
引用本文:宋平顺,晋小军,赵建邦,何禄仁,丁永辉,韩康,鲁静,林瑞超. 不同加工方法对掌叶大黄中蒽醌类和酚酸类成分的影响[J]. 中国现代中药, 2012, 14(6): 46-49
作者姓名:宋平顺  晋小军  赵建邦  何禄仁  丁永辉  韩康  鲁静  林瑞超
作者单位:甘肃省食品药品检验所 甘肃省中药品质与安全评价工程技术研究中心,甘肃 兰州 730000;甘肃农业大学,甘肃 兰州 730050[3.甘肃省食品药品监督管理局,甘肃 兰州 730000;甘肃省食品药品检验所 甘肃省中药品质与安全评价工程技术研究中心,甘肃 兰州 730000;甘肃省食品药品检验所 甘肃省中药品质与安全评价工程技术研究中心,甘肃 兰州 730000;甘肃省食品药品监督管理局,甘肃 兰州 730000;甘肃礼县春天药业有限责任公司,甘肃 礼县 742000;中国食品药品检定研究院,北京 100010;中国食品药品检定研究院,北京 100010
基金项目:“十一五”国家科技支撑计划项目——中药标准物质研制和开发的技术平台(2009ZX09308-001),甘肃省科技重大专项计划项目——当归等八种道地药材的质量标准制订(1002KFDA048)
摘    要:目的:比较熏法、晾法、晒法和烘法对大黄蒽醌类、酚酸类成分的影响,为大黄药材、饮片加工提供依据。方法:采用HPLC分别测定蒽醌类成分、酚酸类成分的含量;并以聚类分析评价。结果:加工方法对大黄中大黄蒽醌类、酚酸类成分有明显影响,传统的熏法中蒽醌类成分含量最高,晾法次之,均可达到《中国药典》的规定,晒法和烘法加工的质量次。结论:熏法推广受到限制,晾法是目前适宜的加工方法。

关 键 词:大黄  产地加工  蒽醌类成分  酚酸类成分  HPLC
收稿时间:2012-01-13

Influence on Content of Anthraquinones,Phenolic Acids by Different Processing Methods in Rhubarb
SONG Ping-shun,JIN Xiao-jun,ZHAO Jian-bang,HE Lu-ren,DING Yong-hui,HAN Kang,LU Jing and LIN Rui-chao. Influence on Content of Anthraquinones,Phenolic Acids by Different Processing Methods in Rhubarb[J]. Modern Chinese Medicine, 2012, 14(6): 46-49
Authors:SONG Ping-shun  JIN Xiao-jun  ZHAO Jian-bang  HE Lu-ren  DING Yong-hui  HAN Kang  LU Jing  LIN Rui-chao
Affiliation:1.Gansu Institute for Food and Drug Control,Gansu Traditional Chinese Medicine Quality and Safety Evaluation Engineering Research Center,Lanzhou 730000,China;2.Gansu Agricultural University,Lanzhou 730050,China;3.Gansu Food and Drug Administration,Lanzhou 730000,China;4.Lixian Gansu spring Pharmaceutical Co.,Ltd.,Lixian 742000,China;5.National Institutes for Food and Drug Control,Beijing 100010,China)
Abstract:Objective:To compare the influences on anthraquinone and phenolic acids in Rhubarb by the different processing technologies,such as drying by smoke,by air,by sunshine and by fire.Methods:HPLC were used to determinate the content of anthraquinones,phenolic acids.Cluster analysis was used to evaluate the quality of processed products.Results:Different processing methods had important influence on content of anthraquinones and phenolic acids in Rhubarb.The processed products of drying by smoke has the highest contents of anthraquinone.The products of drying by air was behind.They can all achieve the standard of Ph.C.The products processed of drying by sunshine method and by fire had poor quality.Conclusion:Compaire with the processed technology of drying by smoke,the technology of drying by air was easier to promotion.
Keywords:Rhubarb  Original  Processing  anthraquinones  Phenolic acids  HPLC
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