| 家族性与散发性精神分裂症中枢5—羟色胺与多巴胺相互作用比较研究 |
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| 引用本文： | 金卫东,臧德馨.家族性与散发性精神分裂症中枢5—羟色胺与多巴胺相互作用比较研究[J].四川精神卫生,2000,13(1):4-5. |
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| 作者姓名： | 金卫东 臧德馨 |
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| 作者单位： | 江苏常州解放军102医院(金卫东!213000，施建安!213000，赵汉清!213000，刘桂永!213000，崔庶!213000)，湖北医科大学附一院(臧德馨) |
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| 摘 要： | 比较家族性与散发性精神分裂症中枢５－ＨＴ与ＤＡ相互作用的差异。方法应用高效液相色谱对２０例家族性和４７例散发性精神分裂症的脑脊液中５－ＨＴ、５－ＨＩＡＡ、ＤＡ、ＨＶＡ进行测试，并以比值作为相作用指标。结论两类型精神分裂症存在着５－ＨＴ与ＤＡ相互作用的差异。
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| 关 键 词： | 精神分裂症 家族史 5－羟色胺 多巴胺 治疗 |
A comparative study on difference in interaction of central serotonin and dopamine between familial and sporadic schizophrenia. |
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| JIN Weidong,ZANG Dexin,SI Jianan,et al..A comparative study on difference in interaction of central serotonin and dopamine between familial and sporadic schizophrenia.[J].Sichuan Mental Health,2000,13(1):4-5. |
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| Authors: | JIN Weidong ZANG Dexin SI Jianan |
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| Institution: | JIN Weidong,ZANG Dexin,SI Jianan,et al.The 102th Hospital of P.L.A. Jiangsu.213000 |
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| Abstract: | Objective To study the difference in interaction of serotonin(5-HT) and dopamine (DA) between familial and sporadic schizophrenia.Methods The levels of 5-HT,5-HTAA,DA and HVA in CSF of 20 familial and 47 sporadic schizophrenic patients were detemined by high pressure liguid chromatography.Results The ratio of 5-HTAA/HVA of familial schizophrenia was significantly higher than that of sporadic schizophrenia.Conclusion The familial schizophrenia and sporadic schizophrenia were different in interaction of central 5-HT and DA. |
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| Keywords: | Schizophrenia Family history 5-HT DA |
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