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通脉降脂口服液治疗动脉粥样硬化的实验研究
引用本文:沈晓君,姬生国. 通脉降脂口服液治疗动脉粥样硬化的实验研究[J]. 河南中医学院学报, 2003, 18(2): 29-30
作者姓名:沈晓君  姬生国
作者单位:[1]河南中医学院,河南省郑州市450008 [2]郑州大学药学院
摘    要:目的:探讨通脉降脂口服液延缓或逆转AS病变的作用。方法:观察通脉降脂口服液对实验性高胆固醇血症鹌鹑动物模型血脂、血浆D-二聚体、第八因子辅因子及主动脉病变的影响。结果:它可使血脂及血浆D-D、VWF水平降低,AS病变明显延缓。结论:通脉降脂口服液除具有良好的调节血脂的作用外,还具有改善内皮细胞功能以及纠正AS时的凝血、纤溶功能紊乱的作用。

关 键 词:通脉降脂口服液 动脉粥样硬化 实验研究 中医药疗法
文章编号:1006-3234(2003)02-0029-02
修稿时间:2002-09-30

Experimental Study of Tongmai Jiangzhi Koufuye in the Treatment of Atheroscleorsis
Shen Xiaojun,JI Shengguo. Experimental Study of Tongmai Jiangzhi Koufuye in the Treatment of Atheroscleorsis[J]. Journal of Henan University of Chinese Medicine, 2003, 18(2): 29-30
Authors:Shen Xiaojun  JI Shengguo
Abstract:Objective: To explore the actions of Tongmai Jiangzhi Koufuye (oral solution) in postponing or reversing the pathological process AS. Method: To observe the effect of this oral solution on blood lipid, plasma D D and VIIIF, and pathologic change of aorta in the duplicated model of quails with experimental hypercholesterolemia. Results: This solution can decrease blood lipid, plasma D D and VWF, and markedly postpone the pathological process AS. Conclusion: Besides the action of regulating blood lipid, this oral solution can also improve the function of endothelial cells, and reverse the disorder of blood coagulation and fibrinolytic function as well.
Keywords:Tongmai Jiangzhi Koufuye  atheroscleorsis  lovastatin  quail
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