| 血清特异性抗HBcIgE的检测及其临床意义 |
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| 引用本文： | 蒋性凡,宋宝崑,杨守纯. 血清特异性抗HBcIgE的检测及其临床意义[J]. 免疫学杂志, 1988, 0(2) |
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| 作者姓名： | 蒋性凡 宋宝崑 杨守纯 |
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| 作者单位： | 解放军302医院免疫研究室 北京(蒋性凡，宋宝崑)，解放军302医院免疫研究室 北京(杨守纯) |
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| 摘 要： | 本文应用ELISA法检测了600例病人及93例献血员血清的特异性抗HBclgE。研究结果证明部分肝炎病人血清中抗HBcIgE效价可高达1:3125～1:78625,HBsAg(RPHA)阳性的急性肝炎,慢性活动性肝炎、慢性迁延性肝炎阳性率分别达到52.6％、69.2％和67.9％,而献血员血清、甲型肝炎病人血清、其他非肝炎病人血清则分别为3.0％,5.5％和0％。两组血清标本之间阳性率有明显差别。可以为乙型肝炎诊断、预后判断和治疗提供参考依据。
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| 关 键 词： | 抗HBcIgE 肝炎 ELISA |
The Detection and Clinical Significance of the Specific Anti-HBcIgE Antibody in Serum |
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| Jiang Xingfan et al. The Detection and Clinical Significance of the Specific Anti-HBcIgE Antibody in Serum[J]. Immunological Journal, 1988, 0(2) |
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| Authors: | Jiang Xingfan et al |
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| Affiliation: | Jiang Xingfan et al Department of Immunology,302 Hospitaf of PLA,Beijing |
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| Abstract: | In this study, ELISA was applied to detect specific anti-HBdgE antibodies in the sera of 600 patients and 93 donors. The results showed that the titer of anti-HBc IgE. antibodies may be high up to 1:3125-78625 in some patients with hepatitis. Among HBsAg positive hepatitis, including acute, active chronic and persistent chronic hepatitis, the positive rates of the anti-HBcIgE were 52.6%, 69.2% and 67.9% separately. However, in the donors and the patients with hepatitis A and with other diseases, the positive rates were 3.0%, 5.5% and 0 % respectively. The difference is significant. It can be provided as a reference basis for the judgement of prognosis and therapeutics. |
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| Keywords: | Anti-HBcIgE antibody Hepatitis ELISA |
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