高血压伴与不伴缺血性脑卒中患者颈动脉内中膜厚度的研究

目的 :用彩色多普勒超声观察高血压伴与不伴缺血性脑卒中患者颈动脉内中膜厚度 ,探讨颈动脉粥样硬化与缺血性脑卒中的关系。方法 :用HDI 30 0 0彩色多普勒超声观察了 36例无缺血性脑卒中的高血压病患者和 36例伴有缺血性脑卒中的高血压病患者双侧颈动脉内中膜厚度 ,并与 2 8名健康对照进行了比较。结果 :1 3组间空腹血糖、血脂和体重指数及平均年龄无显著性差异 (P >0 0 5 ) ;2 单纯高血压病患者和高血压病伴缺血性脑卒中患者颈动脉内中膜厚度明显高于健康对照者 (P <0 0 1) ,且高血压伴缺血性脑卒中患者颈动脉内中膜厚度明显高于无缺血性脑卒中的高血压患者 (P <0 0 1)。结论 :高血压病患者存在有颈动脉粥样硬化 ,且伴有缺血性脑卒中患者颈动脉粥样硬化程度明显加重 ,提示颈动脉粥样硬化程度可作为预测缺血性脑卒中发生的参考指标。

Study of medial-intimal thickening of carotid artery in hypertensive patients with and without ischemic stroke

Objective:To study the media\|intimal thickening of carotid artery in hypertensive patients with and without ischemic stroke by color Doppler ultrasound,and the association of carotid atherosclerosis with ischemic stroke.Method:All patients with essential hypertension were divided into two groups according to the presence of ischemic stroke.There were thirty\|six cases who had no ischemic stroke in the simple hypertension group.There were thirty\|six cases who had ischemic stroke in hypertension with ischemic stroke group.Twenty\|eight controls without coronary,cerebral diseases and diabetes were enrolled.The medial\|intimal thickening of carotid artery in all of the subjects were observed by the ATL HDI 3000 model color Doppler ultrasound.Result:The average medial\|intimal thickening of carotid artery was significantly thicker in the simple hypertension group and in the hypertension group with ischemic stroke than that in control group,and that in hypertension group with ischemic stroke was significantly thicker than in the simple hypertension group.Conclusion:Carotid atherosclerosis was found in hypertensive patients,and severe carotid atherosclerosis was found in hypertensive patients with ischemic stroke.It suggests that the severity of carotid atherosclerosis may be used as a reference index for the prediction of ischemic stroke.