丹参注射液联合激素治疗肾病综合征临床观察

目的：评价丹参注射液联合激素治疗肾病综合征（NS）的临床疗效。方法：将60例NS患者以随机数字表法分为两组,各30例。对照组采用足量强的松及常规治疗。治疗组在足量强的松及常规治疗基础上加用丹参注射液静脉滴注,两组疗程均为4周。分别观察两组治疗前后尿常规、血脂系列、24 h尿蛋白定量等指标变化。结果：治疗后两组患者24 h尿蛋白定量较治疗前均明显降低,治疗组总有效率为93.3%,对照组为75.0%（P〈0.05）。治疗组治疗后血脂、血液流变学、肾功能等指标较治疗前均有显著改善,与对照组比较差异有显著性意义（P〈0.05）。结论：丹参注射液联合激素能显著提高肾病综合征的疗效。

"Danshen Injection" plus Prednisone for Nephrotic Syndrome

Objective:To assess the efficacy of "Danshen Injection" combined with prednisone for nephrotic syndrome(NS).Methods:Sixty patients with NS were randomized into two groups.Thirty patients in control group were treated with full dosage of prednisone and conventional therapy,thirty patients in treatment group received full dosage of prednisone,conventional therapy and intravenous "Danshen Injection".Urine routine test,blood fat and 24-hour urine protein were detected.Results:24-hour urine protein in patients of both groups were all decreased;total effective rate was 93.3% in treatment group and 75.0% in control group.As compared with control group,blood fat,hemorheology and renal function in treatment group were improved significantly(P < 0.05).Conclusion:"Danshen Injection" combined with prednisone may improve NS.