Metabolic scaling law for mouse fetal and placental weight |
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| Authors: | M Gasperowicz M Yampolsky CM Salafia |
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| Institution: | 1. Department of Comparative Biology and Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada;2. Department of Mathematics, University of Toronto, 40 St. George Street, Toronto, Ontario M5S 2E4, Canada;3. Placental Analytics, LLC, Larchmont, NY, USA |
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| Abstract: | Human birth weight does not scale linearly with the weight of the placenta: placental mass (PM) is proportional to the fetal mass (FM) raised to the scaling exponent of 0.75 (PM ∼ FM0.75) 1 and 2. The mouse is a common model for studying genetic and physiological backgrounds of placental development, function and pathologies. However, to date it has not been known how placental weight scales relative to embryo weight in mice. |
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| Keywords: | Allometric scaling Metabolic efficiency |
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