Further evidence of human αa-l-fucosidase polymorphism

The results of a comparative study of multiple forms of α-l-fucosidase from human kidney, liver, placenta and blood serum provide evidence for α-l-fucosidase polymorphism. On the basis of the data obtained the existence of certain phenotypic groups of α-l-fucosidase, dissimilar both in the quantitative and qualitative composition of the enzyme's multiple forms, was revealed. Some possible reasons for α-l-fucosidase polymorphism are discussed. It is suggested that the data on α-l-fucosidase polymorphism may be used in diagnosis and in the isolation and preparation of individual enzyme forms.