二维及三维超声诊断胎儿全前脑并面部畸形

目的 探讨二维及三维超声诊断胎儿全前脑并面部畸形的临床价值。方法 二维超声疑脑部异常者常规进行胎儿面部及脑部三维重组，将诊断结果与产后或引产后进行对照分析。结果 利用二维及三维超声诊断了11例全前脑并面部畸形，其中全前脑并单鼻孔4例，全前脑并喙鼻2例，全前脑并唇裂2例，全前脑并面部复合畸形2例，全前脑并无鼻1例，均经引产后证实。结论 三维超声提供了直观、立体、逼真的胎儿结构图像，对二维图像具有重要的补充作用，两者联合应用可提高胎儿全前脑并面部畸形的诊断率。

Diagnostic value of two-dimensional and three-dimensional ultrasonography in detecting fetal holoprosencephaly complicated with face malformation

Objective To evaluate the clinical value of fetal holoprosencephaly complicated with face malformation by two-dimensional(2D) and three-dimensional(3D) ultrasonography.Methods Fetal faces and brains were examined regularly with 3D ultrasonography when they were suspected abnormal with 2D ultrasonography and compaired the diagnoses with postnatal or induced delivery results.Results 11 cases of holoprosencephaly complicated with face malformation were diagnosed using 2D and 3D ultrasonography.Among these cases,there were 4 with single median mostril,2 with proboscis,2 with cheiloschisis,2 with multipte face malformation,1 with arhinia.They were all comfirmed by postnatal or induced delivery.Conclusions 3D ultrasonography provides visualized,three-dimensional,more precise and clearly fetal structure imagine.It has important supplement to 2D ultrasonography.2D ultrasonography combined with 3D ultrasonography can greatly enhance the diagnosis rate to holoprosencephaly complicated with face malformation.