| 帕金森病脑深部灰质核团MR T_2值的初步研究 |
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| 引用本文： | 汤敏,焦俊,沈桂权,魏渝清,洪早云.帕金森病脑深部灰质核团MR T_2值的初步研究[J].临床放射学杂志,2010,29(3). |
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| 作者姓名： | 汤敏 焦俊 沈桂权 魏渝清 洪早云 |
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| 作者单位： | 1. 陕西省人民医院CT、MRI室,710068
2. 贵阳医学院第一附属医院放射科,550004 |
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| 摘 要： | 目的探讨脑深部灰质核团MRT2值在帕金森病(PD)中的诊断价值及意义。资料与方法选取PD患者20例和对照组10名,分别对黑质、红核、尾状核、壳核、丘脑进行MRI扫描,根据Block方程求T2值,对两组各核团T2值采用成组设计定量资料是否呈正态分布、方差是否齐性,选择t检验、近似t检验;PD患侧黑质T2值与疾病分期进行相关分析;采用随机成组设计对不同分期(1～2期、2.5～3期、4期)PD组患侧感兴趣区(ROI)T2值进行组间比较,P<0.05有统计学意义。结果(1)20例PD组患侧黑质与10名对照组黑质T2值比较有统计学意义(P<0.05),PD组黑质T2值(29.65±3.41)较对照组黑质T2值(32.45±1.78)明显减低;PD组患侧红核、尾状核、壳核及丘脑ROI与对照组ROI无明显统计学意义(P>0.05)。(2)PD组患侧黑质T2值与疾病不同分期呈负相关性(r=-0.733)。(3)不同分期(1～2期、2.5～3期、4期)PD组患侧黑质T2值有统计学意义(P<0.05),且T2值逐渐减低;壳核在2.5～3期与4期有统计学意义(P<0.05),且表现为2.5～3期T2值减低(31.74±2.80),...
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| 关 键 词： | 帕金森病 磁共振成像 T_2值 铁 |
Study on T_2 Value of MRI in Brain of Deep Gray Nucleus with Parkinson's Disease |
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| TANG Min,JIAO Jun,SHENG Guiquan,et al..Study on T_2 Value of MRI in Brain of Deep Gray Nucleus with Parkinson's Disease[J].Journal of Clinical Radiology,2010,29(3). |
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| Authors: | TANG Min JIAO Jun SHENG Guiquan |
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| Institution: | TANG Min,JIAO Jun,SHENG Guiquan,et al.Department of Imaging,the First Affiliated of Guiyang University,Guiyang,Guizhou 550004,P.R.China |
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| Abstract: | Objective To study the significance of MRI T2 Values of brain deep gray nucleus in diagnosis of Parkinson's disease.Materials and Methods Twenty cases of the PD with clear diagnosis and the 10 normal controls were collected in our study.All the cases performed MRI scan with the same repetition time and two different echo times to obtain the T2 weighted imaging.Signal intensity of each ROI was measured and T2 value was calculated using Block equations.Results (1) T2 values of substantia nigra were significan... |
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| Keywords: | Parkinson's disease Magnetic resonance imaging T2 values Iron |
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