| 幽门螺杆菌感染与抑郁症的关联性研究 |
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| 引用本文： | 陈渭,黄文柱,郭锦滔,陈广辉.幽门螺杆菌感染与抑郁症的关联性研究[J].吉林医学,2011,32(13):2509-2510. |
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| 作者姓名： | 陈渭 黄文柱 郭锦滔 陈广辉 |
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| 作者单位： | 广东省佛山市第五人民医院消化内科;广东省佛山市第五人民医院精神心理科; |
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| 摘 要： | 目的:探讨幽门螺杆菌(Hp)与抑郁症是否具有关联性,Hp根除治疗对抑郁症患者病情的影响。方法:抑郁症患者共131例,行14C-尿素呼气试验分为Hp感染组(101例)和未感染组(30例),使用汉密尔顿(HAMD)抑郁量表进行抑郁评分。Hp感染组随机分为试验组(55例)和对照组(46例),试验组进行规范Hp根除治疗,两组同时依病情使用SSR、ISNR I及NaSSA类抗抑郁药,4周后再次行HAMD抑郁评分。结果:Hp感染组与非感染组HAMD抑郁评分分别为26.55±5.94、17.90±5.65,t=7.085,P=0.000。试验组与对照组治疗前后HAMD抑郁评分差值分别为9.27±7.73、4.93±5.00,t=3.398,P=0.001。结论:幽门螺杆菌感染与抑郁症相关,Hp根除治疗对抑郁症患者的病情好转有显著促进作用。
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| 关 键 词： | 幽门螺杆菌 抑郁症 |
Association between Helicobacter pylori infection and depression |
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| CHEN Wei,HUANG Wen-zhu,GUO Jin-tao,et al.Association between Helicobacter pylori infection and depression[J].Jilin Medical Journal,2011,32(13):2509-2510. |
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| Authors: | CHEN Wei HUANG Wen-zhu GUO Jin-tao |
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| Institution: | CHEN Wei,HUANG Wen-zhu,GUO Jin-tao,et al(The Fifth People's Hospital of Foshan City,Foshan 528211,China) |
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| Abstract: | Objective To investigate the relationship between Helicobacter pylori(Hp) infection and depression,and the effect of Hp eradication therapy on the conditions of depression.Method Total 131 patients with depression were divided into two groups: the Hp infection group(n=101) and the normal group(n=30) by 14C-UBT.They were appraised by Hamilton Depression Rating Scale(HAMD). The Hp infection group was randomized into the experimental group(n=55) and the control group(n=46).The experimental group accepted Hp er... |
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| Keywords: | Helicobacter pylori Depression |
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