革兰阴性菌耐药性分析

目的:监测革兰阴性细菌耐药状况,为指导临床抗生素合理应用提供依据。方法:对从临床各类送检标本进行培养分离鉴定,对分离到的革兰阴性菌采用K-B法进行抗生素敏感实验。结果:共分离到302株革兰阴性细菌,其中分离第一位的是大肠埃希菌(95株),其次是肺炎克雷伯(40株)、铜绿假单胞菌(35株)和鲍曼不动杆菌(26株)。大肠埃希菌耐药性比较严重,对喹诺酮中的环丙沙星和三代头孢菌素耐药性都在60%以上,大肠埃希菌和肺炎克雷伯菌产ESBLs比率分别为64.8%和41.3%。铜绿假单胞菌对碳青霉烯类的敏感性仍保持在80%以上,鲍曼不动杆菌对大多数药物敏感率低于50%。结论:细菌耐药情况普遍存在,应引起医疗单位和管理部门的高度重视。

Analysis of gram-negtive bacteria resistant situation in Huangshi hospital of Chinese medicine in 2010

Objective To monitor gram-negtive bacteria resistant situation in 2010,to offer evidence for clinical reasonable antibiotics usage.Methods All clinical secimas were isolated and cultured and identified in 2010.Positive bacteria use K-B doing drug-sensitive test according to CLSI 2009.Results 302 strains bacteria were isolate.The first frequent bacteria was E.coli(95 strains).Klebsiella pneumoniae(64 strains),Pseudomonas.aeruginosa(45 strains),Acinetobacter baumannii(36 strains),respectively.The drug-resista...