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甲状腺激素与癌症的相关性研究进展
引用本文:刘合代,余志银,孙利国.甲状腺激素与癌症的相关性研究进展[J].中国优生与遗传杂志,2020(1):115-118.
作者姓名:刘合代  余志银  孙利国
作者单位:上海交通大学医学院附属新华医院崇明分院肿瘤科;定西市中西医肿瘤研究所;东北农业大学生命科学院;定西市人民医院肿瘤科
摘    要:肿瘤患者甲状腺激素(T3)的代谢会产生异常,在肿瘤浸润深、淋巴结受累多、分期晚、病情重的患者中T3会显著下降。同时肿瘤的治疗(手术、放疗、化疗、靶向治疗、免疫治疗)也会造成T3下降。肿瘤患者T3的改变可以作为判断病情及临床分期、监测疗效、维护生活质量的参考指标,受到临床医生越来越多的关注。

关 键 词:甲状腺激素  3  5-3-三碘甲状腺原氨酸  癌症  研究进展

Advances in research on the relationship between thyroid hormone and cancer
LIU He-dai,YU Zhi-yin,SUN Li-guo.Advances in research on the relationship between thyroid hormone and cancer[J].Chinese Journal of Birth Health & Heredity,2020(1):115-118.
Authors:LIU He-dai  YU Zhi-yin  SUN Li-guo
Institution:(Department of Oncology,Chongming Branch,Xinhua Hospital,Shanghai Jiao tong University School of Medicine,Chongming,Shanghai 202150;Dingxi Oncology Institute of Traditional Chinese and Western Medicine,Dingxiy Gansuy 734000;College of Life Sciences,Northeast Agriculture University,Harbin,150030;Department of Oncology,Dingxi People′s Hospital of Gansu Province,Dingxi,Gansu,743000)
Abstract:The metabolism triiodothyronine(T3)in thyroid hormone of tumor patients will be abnormal,and T3 will decrease significantly in patients with deep tumor infiltration,multiple lymph node involvement,late stage and severe disease.At the same time,the treatment of tumors(surgery,radiotherapy,chemotherapy,targeted therapy,immunotherapy)will also lead to the decrease of T3.The change of T3 in cancer patients can be used as a reference index for judging the condition and clinical stage,monitoring the curative effect and maintaining the quality of life,which has attracted more and more attention from clinicians.
Keywords:Thyroid hormone  Triiodothyronine  Cancer  Research advances
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