新疆不同民族慢性心力衰竭患者凝血因素与中医证型的关系研究

目的:研究新疆地区不同民族慢性心力衰竭(CHF)患者凝血功能、血脂、同型半胱氨酸与中医证型的相关性.方法:对400例新疆地区不同民族CHF患者凝血功能、血脂、同型半胱氨酸等实验室指标进行临床流行病学调查,总结CHF的中医证型分布规律.结果:(1) CHF患者存在血栓前状态.(2)CHF患者中出现例数最多的中医证型是痰瘀互结证和气虚血瘀证;少数民族CHF患者中证型分布最多的是痰瘀互结证,其次为气虚血瘀证.(3)血脂变化最明显的CHF患者中医证型以痰瘀互结为多见,气虚血瘀证次之.(4) CHF患者随着心功能由Ⅱ级到Ⅳ级,D-二聚体变化呈明显趋势.结论:新疆少数民族CHF患者中以痰瘀互结证型最为多见,且血脂、同型半胱氨酸异常在痰瘀互结证者中也多见.

Chronic heart failure patients of different ethnic groups in Xinjiang clotting factors and TCM syndrome type of discussion

Objective: To study the correlation of blood lipid,blood clotting and homocysteine in different ethnic groups of chronic heart failure patients with TCM syndrome type.Methods: 400 cases of patients with heart failure were investigated,whose blood clotting,blood fat,homocysteine and every syndrome type were statistically analyzed.Results:(1) There was pre-thrombosis state in patients with chronic heart failure.(2) TCM syndromes of mutual phlegm and blood stasis syndrome and qi and blood stasis syndrome were most frequently seen in patients with chronic heart failure;minority chronic heart failure patients more likely encountered the latter.(3) Chronic heart failure patients with obvious changes of blood lipid had phlegm and blood stasis TCM syndrome more than blood stasis syndrome.(4) D-dimer increased remarkably along with cardiac function classification in chronic heart failure patients.Conclusion: Phlegm and blood stasis syndrome is frequently observed in Xinjiang’s ethnic minority patients with chronic heart failure;while phlegm and blood stasis syndrome is found mostly in patients with abnormal blood fat,homocysteine.