| 枳棋子乙酸乙酯提取物对小鼠耐缺氧能力及糖原含量影响实验研究 |
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| 引用本文： | 伊佳,嵇扬,刘俊,王文俊,高锦,沈娟,聂渝琼,周苏萍.枳棋子乙酸乙酯提取物对小鼠耐缺氧能力及糖原含量影响实验研究[J].解放军药学学报,2009(2):130-132. |
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| 作者姓名： | 伊佳 嵇扬 刘俊 王文俊 高锦 沈娟 聂渝琼 周苏萍 |
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| 作者单位： | [1]第二军医大学,上海200433 [2]总后勤部卫生部药品仪器检验所,北京100071 |
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| 摘 要： | 目的观察枳棋子乙酸乙酯提取物对小鼠耐缺氧及糖原含量的影响。方法昆明小鼠随机分为5组，分别为空白对照组、诺迪康胶囊阳性组及枳棋子乙酸乙酯提取物高、中、低（60、30、15mg·kg^-1）3个剂量组，连续给药数天后作相关指标检测。结果枳棋子乙酸乙酯提取物能显著延长小鼠缺氧状态存活时间并且增加糖原含量。结论枳棋子乙酸乙酯提取物具有良好的耐缺氧作用，并且能够增加机体糖原含量。
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| 关 键 词： | 枳棋子 乙酸乙酯提取物 缺氧 糖原 |
A Study on the Effect of Hovenia Dulcis Thunb Ethyl Acetate Extracts on the Action of Anti-hypoxia Capacity and the Storage of Glycogen in Mice |
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| YI Jia,JI Yang,LIU Jun,WANG Wen-Jun,GAO Jin,SHEN Juan,NIE Yu-Qiong,ZHOU Su-Ping.A Study on the Effect of Hovenia Dulcis Thunb Ethyl Acetate Extracts on the Action of Anti-hypoxia Capacity and the Storage of Glycogen in Mice[J].Pharmaceutical Journal of Chinese People's Liberation Army,2009(2):130-132. |
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| Authors: | YI Jia JI Yang LIU Jun WANG Wen-Jun GAO Jin SHEN Juan NIE Yu-Qiong ZHOU Su-Ping |
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| Institution: | 1The Sencond Military Medical University,Shanghai 200433 China;2Institute for Drug and Instrument Control of Health Department GLD of PLA ,Beijing 100071 China) |
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| Abstract: | Aim To investigate the effect of Hovenia dulcis Thunb ethyl acetate extracts on the action of anti-hypoxia and increase of glycogen storage. Methods KM mice were randomly divided into five groups： control group, positive control group （Rhodiala）, the low, middle and high dosage groups （60,30,15mg·kg^-1）. Days later, a corresponding test was conducted. Results Hovenia dulcis Thunb ethyl acetate extracts could prolong the survival time of mice in hypoxia and increase the storage of glycogen. Conclusion Hovenia dulcis Thunb ethyl acetate extracts are effective for anti-hypoxia and glycogen storage. |
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| Keywords: | Hovenia dulcis Thunb ethyl acetate extracts anti-hypoxia glycogen |
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