恶性肿瘤患者血液流变学临床观察

目的 :探讨恶性肿瘤与血液流变学的关系。方法 :对恶性肿瘤患者 44例与健康人42例的血液流变学进行观察分析。结果 :恶性肿瘤患者的红细胞沉降率、血浆粘度、血栓长度、血小板粘附率均高于正常组 (P <0 0 1 ) ;血细胞比容低于正常对照组 (P <0 0 1 ) ;血栓湿重明显高于正常组 (P <0 0 1 ) ;有显著性差异 ,晚期转移组的红细胞沉降率 ,血浆粘度高于非转移组 (P <0 0 5 ) ;血细胞比容低于非转移组 (P <0 0 1 )。结论 :恶性肿瘤患者存在着明显的血液流变学异常 ,晚期患者尤其明显 ,提示恶性肿瘤患者处于高粘、高凝状态 ,检测血液流变学对判断病情预测、预后有一定意义 ,改善血液粘滞状态可以延缓病情 ,防止转移 ,预防血栓并发症发生

Clinical Observation of Hemorheology of Malignant Tumor Patients

Objective:to discuss the relationship between the malignant tumor and blood rheologu.Methods:the rheology data of 44 cases of malignant tumor patients and 42 healthy adults were analyzed.Results:The ESR,viscosity,length and met weight of thrombosis and adhesive rate of platelet were higher than normal group (p<0.01).HCT was lower than normal group and there was significant differenct.The ESR and viscosity in late metastasis group were higher than those in non-metastasis group(p<0.05).The HCT was lower in late metastasis group than that in nonmetastasis group(p<0.01).Conclusions:There were obvious abnormalities of blood rheology in malignant tumor patients especially in late stage. There indicated that malignant tumor patient was in hyperviscosity and hypercoagulability status. The detection of rheology could predict the situation and prognosis of patients. Improvement of viscosity could prolong the severith,prevent metastasis and thrombosis complications.