Evidence for the existence of genetically distinct strains of Enterocytozoon bieneusi |
| |
| Authors: | H Rinder S Katzwinkel-Wladarsch T Löscher |
| |
| Institution: | Abteilung für Infektions- und Tropenmedizin, Universit?t München, Leopoldstrasse 5, D-80802 München, Germany Fax: +49 89-336112, DE
|
| |
| Abstract: | Enterocytozoon bieneusi is the most frequently found microsporidium in human infections. In all, 3 distinct genotypes were detected in 12 stool samples
from 8 patients with acquired immunodeficiency syndrome (AIDS). A total of 9 polymorphic sites were found in the 243-bp-long
internal transcribed spacer (ITS) of the rDNA gene, whereas none was found in 241 bp of adjacent rRNA coding regions. The
genotype was stable in samples taken during 11 weeks of infection from one of the patients. The existence of and the ability
to discriminate among strains of E. bieneusi are important prerequisites for elucidation of the hitherto unknown reservoirs of this pathogen and the mode of its transmission
and may explain its pathogenicity.
Received: 18 March 1997 / Accepted: 10 April 1997 |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
