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系数倍率法测定甲硫霜的含量
引用本文:莫明兴,费寿耆. 系数倍率法测定甲硫霜的含量[J]. 药学与临床研究, 2004, 12(1): 23-24
作者姓名:莫明兴  费寿耆
作者单位:常州市第一人民医院,常州,213003
摘    要:目的 建立一种同时测定制剂中多组分含量的分光光度法。方法 采用系数倍率法不经分离直接测定霜剂中甲硝唑及升华硫的含量 ,测定波长为 3 15 4nm和 2 81 6nm。结果 甲硝唑的平均回收率及RSD为 10 0 2 %、0 62 % ;升华硫的平均回收率及RSD为 10 0 5%、1 0 3 %。结论 本法操作简便、快速、准确 ,适宜医院作为内控的制剂分析

关 键 词:系数倍率法  甲硝唑  升华硫
文章编号:1007-306(2004)01-23-02
修稿时间:2003-07-21

Determination of Metronidazole and Sublimed Sulfur in Cream by K-ratio Method
Mo Ming-xing,Fei Shou-qi The First People''''s Hospital of ChangZhou. Determination of Metronidazole and Sublimed Sulfur in Cream by K-ratio Method[J]. Pharmacertical and Clinical Research, 2004, 12(1): 23-24
Authors:Mo Ming-xing  Fei Shou-qi The First People''''s Hospital of ChangZhou
Affiliation:ChangZhou213003
Abstract:ObjectiveTo establish a method o f spectrophotometry for simultaneously determination of multi-compounds in prepor ation Methodk-ratio method was used without separation The deter mination wavalength ware at 315 4 nm,281 6 nm respectively ResultThe average recovery of metronidazole was 100 2%,RSD 0 62% and average recovery of sublimed sulfur was 100 5%, RSD 1 03% ConclusionThis determination method is simple,rapid,accurate and suita ble fo r hospital pharmacy
Keywords:K-ratio method  Metronidazole  Sublimed sulfur
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