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阿斯匹林对小鼠乳腺癌细胞株的抑制作用
引用本文:杨勤. 阿斯匹林对小鼠乳腺癌细胞株的抑制作用[J]. 贵州医药, 2000, 24(5): 282-283
作者姓名:杨勤
作者单位:贵阳医学院病理生理教研室,550004
摘    要:目的 观察阿斯匹林在体外对小鼠乳腺癌细胞株有无确切的抑制作用。方法 将小鼠乳腺癌细胞株(HC-11)与不同浓度的阿斯匹林共同培养,于培养后24、48、72小时分别作细胞计数,并计算IC50。结果 阿斯匹林对HC-11有明确的生长抑制作用,且此作用与阿斯匹林的用量呈明显正相关。结论 提示阿斯匹林在乳腺癌的化学预防方面有一定的应用前景。

关 键 词:阿斯匹林 乳腺癌 药物疗法 实验研究

Study of aspirine inhibiton on mice mammary cancer cells
Yang Qin. Dept. of Pathology and physiology of Guiyang Medical College,Guiyang. Study of aspirine inhibiton on mice mammary cancer cells[J]. Guizhou Medical Journal, 2000, 24(5): 282-283
Authors:Yang Qin. Dept. of Pathology  physiology of Guiyang Medical College  Guiyang
Affiliation:Yang Qin. Dept. of Pathology and physiology of Guiyang Medical College,Guiyang 550004
Abstract:Objective To observe inhibition of aspirine to mice mammary cancer cells(HC 11).Methods The HC 11 was incubated with aspirine of different concentration. The number of cells were counted at 24hs, 48hs and 72hs were calculated IC50 respectively.Results Aspirine had a clear inhibited to HC 11 growing. A concentration dependent reduction in the HC 11 number was ovserved in response to aspirine treatment.Conclusion Aspirine can be used as preventive medicine in mammary cancer.
Keywords:Aspirine Mammary cancer
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