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解析医院开展药物警戒的重要性
引用本文:崔岚,傅文,但国群. 解析医院开展药物警戒的重要性[J]. 中国药物警戒, 2010, 7(11): 670-673
作者姓名:崔岚  傅文  但国群
作者单位:1. 昆明医学院第二附属医院,云南,昆明,650101
2. 云南省药品不良反应监测中心,云南,昆明,650101
3. 昆明医学院药学院实习生,云南,昆明,650031
摘    要:目的了解医院药品不良反应/事件(ADR/ADE)发生)特点及一般规律,为临床合理用药提供参考。方法采用回顾性研究方法,对某医院2006年1月至2008年12月收集到的237份ADR/ADE报告表进行统计分析。结果在237例ADR/ADE报告中,大于60岁年龄组的不良反应居首位,占24.47%;抗微生物药物不良反应居首位,占56.92%;静脉滴注给药引起的ADR/ADE居首位,占75.10%;不良反应的临床表现以皮肤及其附件损害最多,占39.18%。结论 ADR/ADE监测是医院的重要工作,开展药物警戒是患者用药安全的保障。

关 键 词:药品不良反应/事件(ADR/ADE)  分析  药物警戒

Analysis of Significance of Pharmacovigilance in Hospital
CUI Lan,FU Wen,DAN Guo Qun. Analysis of Significance of Pharmacovigilance in Hospital[J]. Chinese JOurnal of Pharmacovigilance, 2010, 7(11): 670-673
Authors:CUI Lan  FU Wen  DAN Guo Qun
Affiliation:1The Second Affiliated Hospital of Kunming Medical College,Yunnan Kunming,650101,China;2The ADR Monitoring Center of Yunnan Province,Yunnan Kunming,650101,China;3Trainee in School of Pharmaceutical Sciences Kunming Medical College,Yunnan Kunming,650031,China)
Abstract:Objective By analyzing the characteristicsand regulars of adverse drug reaction/event(ADR/ADE) occurred in one hospital,to provide reference for clinical rational drug use.Methods To adopt the reviewing analytical method to count up and analyze 237 cases ADR/ADE report,these ADR/ADE reports were received from Jan.2006 to dec.2008 by one hospital.Results Out of the 237 cases ADR/ADE reports,58 showed ADR among the over 60 year old group,amount to 24.47%.Leading the list were antibiotics(56.92%).The clinical expression of ADR is showed mostly skin and appendix harms,amount to 39.18%.The suspected ADR cases induced by intravenous route were most common,amount to 75.10%.Conclusion ADR monitoring is an important work for medical institutions,and pharmacovigilance is conducive to patients' medication safety.
Keywords:adverse drug reaction/event(ADR/ADE)  analysis  pharmacovigilance
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