| 感冒清口服液澄清工艺的研究 |
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| 引用本文： | 卫世杰,霍务贞.感冒清口服液澄清工艺的研究[J].药学与临床研究,2012,20(3):267-269. |
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| 作者姓名： | 卫世杰 霍务贞 |
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| 作者单位： | 1. 广东药学院药科学院
2. 广东药学院中药开发研究所,广州,510006 |
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| 基金项目： | 广东省医学科研基金项目，广东省中医药管理局课题 |
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| 摘 要： | 目的:探索感冒清口服液最佳澄清工艺。方法:比较5种澄清工艺对感冒清口服液中总多糖含量、水浸出物的重量和外观澄清度,并对最佳工艺的作用条件进行了考察。结果:壳聚糖沉淀法对多糖含量影响较小,水浸出物的重量较低,外观澄清,效果较佳;壳聚糖用量为5%、溶液pH 5的条件下,澄清效果较好,残留量也较低。结论:壳聚糖沉淀法为感冒清口服液最佳澄清工艺。
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| 关 键 词： | 感冒清口服液 壳聚糖 吸附技术 残留量 |
| 收稿时间： | 2012/3/23 0:00:00 |
| 修稿时间： | 2012/3/30 0:00:00 |
Study on Clarification Process of Ganmao-Qing Oral Liquid |
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| WEI Shi-jie and HUO Wu-zhen.Study on Clarification Process of Ganmao-Qing Oral Liquid[J].Pharmacertical and Clinical Research,2012,20(3):267-269. |
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| Authors: | WEI Shi-jie and HUO Wu-zhen |
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| Institution: | 1Department of Pharmaceutics,Guangdong Pharmaceutical University; 2Research & Development Institute of Chinese Materia Medica,Guangdong Pharmaceutical University,Guangzhou 510006,China |
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| Abstract: | Objective: To optimize the purification process of Ganmao-Qing oral liquid.Methods: By determining dry extract,total polysaccharide content and clarity degree,five clarification processs were compared.The optimum conditions were also investigated.Results: Chitosan adsorption technic had little influence on total polysaccharide content and could reduce the weight of dry extract.High clarity degree and low residue was achieved with 5%,chitosan solution at pH 5.Conclusion: Chitosan adsorption clarification technic can be used as the clarification process of Ganmao-Qing oral liquid. |
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| Keywords: | Ganmao-Qing oral liquid Chitosan Clarification process Residue |
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