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Les manifestations des infections liées au cathéter chez les patients en nutrition parentérale à domicile
Authors:Madeleine Lauverjat  Catherine Peraldi  Patrick Gelas  Cécile Chambrier
Institution:1. Department of neurosurgery, groupe hospitalier universitaire de La Pitié-Salpêtrière, 47-83, boulevard de l’Hôpital, 75013 Paris, France;2. Department of epileptology, groupe hospitalier universitaire de La Pitié-Salpêtrière, 47-83, boulevard de l’Hôpital, 75013 Paris, France;1. Département d’anesthésie-réanimation chirurgicale, CHRU de Brest, 29609 Brest cedex, France;2. Service de réanimation médicale, CHRU de Brest, 29609 Brest cedex, France;3. Département d’anesthésie-réanimation, HIA Clermont-Tonnerre, 29240 Brest cedex 9, France;1. Service d’anesthésie réanimation, centre hospitalier Princesse-Grâce, avenue Pasteur, 98000 Monaco;2. Unité de chirurgie ambulatoire, département d’anesthésie réanimation, hôpital Saint-Antoine, AP–HP, 184, rue du Faubourg-Saint-Antoine, 75571 Paris cedex 12, France;3. Paradigm Healthcare Consulting and Management, chemin Gino-Niccolai, 06100 Nice, France;4. AP–HP, hôpital Saint-Antoine, 184, rue du Faubourg-Saint-Antoine, 75571 Paris cedex 12, France;1. Apard groupe Adène HAD Montpellier, 69, rue Jean-Giroux, 34080 Montpellier, France;2. Cicat-Occitanie, hôpital Lapeyronie, UMPC, 371, avenue du Doyen-Gaston-Giraud, 34000 Montpellier, France;3. Clinique du Parc, 50, rue Émile-Combes, 34170 Castelnau-le-Lez, France
Abstract:ObjectiveManifestations of catheter-related infections (CRI) can be various; we studied the symptoms leading to the diagnosis.MethodsDuring 14 months, we have identified clinical and laboratory manifestations and germs responsible. The results are expressed either as a percentage or median and comparisons with Fisher's exact test.ResultsForty-nine patients out of 192 presented 60 episodes of CRI. For 75%, fever and/or chills during the infusion led to a rapid diagnosis. For 25% of cases, the ILC has been evocated after receiving a biological balance disturbed (16.7%) or found during hospitalization for another reason (8.3%). In 73.3% of cases, a history of fever and/or chills was then found, without alerting the patient. Other symptoms, which were sometimes the warning signs were headache (45%), myalgia (40%), gastrointestinal symptoms (33.3%) and hypotension (20%). Laboratory abnormalities were elevated CRP (86.4%), decreased lymphocytes (59.6%), a change in platelets (43.3%) or leukocytes (40%), renal impairment (45%) and liver (37.5%). Gram-negative bacilli were more often responsible for typical forms as gram-positive cocci were isolated in 86.7% of rough forms (P < 0.000).ConclusionsA CRI can manifest by other clinical signs as fever and/or chills. Biological monitoring can sometimes detect crude forms. Educating patients is crucial to learn the early diagnosis of ILC in home parenteral nutrition.
Keywords:Catheter-related infection  Home parenteral nutrition  Manifestations
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