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A case series of paediatric high flow nasal cannula therapy
Authors:Sara Mayfield  Jacqueline Jauncey-Cooke  Fiona Bogossian
Affiliation:1. Paediatric Intensive Care Unit, Mater Children''s Hospital Brisbane, PICU, Australia;2. School of Nursing and Midwifery, The University of Queensland, Australia;1. State Key Laboratory of Trauma, Burns and Combined Injury, Second Department of Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, P. R. China;2. Department of Anesthesiology, Daping Hospital, Third Military Medical University, Chongqing, P. R. China;1. Department of Pharmaceutical Sciences, Chicago College of Pharmacy, Midwestern University, Downers Grove, Illinois;2. Division of Pediatric Critical Care, Advocate Lutheran General Hospital, Park Ridge, Illinois;1. Michael E. DeBakey Department of Surgery, Section of Infectious Disease, Baylor College of Medicine, One Baylor Plaza, N-1318, Houston, TX 77007, USA;2. Department of Medicine, Section of Infectious Disease, Baylor College of Medicine, Houston, TX, USA;1. Department of Radiology, Erciyes University Medical Faculty, Kayseri, Turkey;1. Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia;2. Australia and New Zealand Intensive Care Research Centre, School of Public Health and Preventative Medicine, Monash University, Melbourne, Victoria, Australia;3. Pharmacy Department, Alfred Health, Melbourne, Victoria, Australia;4. Intensive Care Unit, Alfred Health, Melbourne, Victoria, Australia;5. Intensive Care Unit, The Austin Hospital, Heidelberg, Victoria, Australia
Abstract:IntroductionHigh flow nasal cannula is an emerging treatment option in Paediatric Intensive Care Units for paediatric patients in acute respiratory distress. Yet there is a paucity of literature describing its clinical application in various presenting pathophysiologies.AimTo describe three cases with differing underlying pathophysiologies and their response to high flow nasal cannula oxygen therapy.MethodPatients admitted to the Paediatric Intensive Care Unit with bronchiolitis, asthma and cardiomyopathy, and treated with high flow nasal cannula therapy were searched in the Paediatric Intensive Care database. The most representative cases were chosen to review.ResultsOne infant and two children were reviewed. All were commenced on high flow nasal cannula therapy in the Paediatric Intensive Care Unit and all demonstrated an improvement in their work of breathing. There was also a substantial improvement in their haemodynamic status. No patient required escalation to other forms of respiratory therapy.ConclusionHigh flow nasal cannula therapy is a viable treatment option for a range of patients presenting to the Paediatric Intensive Care Unit with acute respiratory distress. More invasive methods of respiratory support may be avoided by the use of high flow nasal cannula therapy.
Keywords:High flow nasal cannula  Bronchiolitis  Asthma  Cardiomyopathy  Infants  Children
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