医用臭氧在皮肤疾病中的创新性应用

自19世纪中期人们发现了臭氧，臭氧的多种治疗作用已被广泛接受并常用于杀菌消毒。一个多世纪的研 究表明臭氧在实施多种治疗作用的同时，其毒副作用完全可控。近期的研究更证明了臭氧在感染性皮肤病、皮炎湿 疹类皮肤病及皮肤慢性溃疡等疾病中的治疗作用。本课题组将臭氧广泛应用于治疗多种皮肤疾病，并致力于研究医 用臭氧的疗效和安全性。此外本文也讨论了臭氧治疗的可能作用机制和未来的研究方向。

Emerging roles of ozone in skin diseases

Ozone was discovered in the mid-nineteenth century and is proven to have many therapeutic effects, including its common application as a disinfectant to kill microorganisms in various conditions. Ozone therapies have been utilized for various purposes ever since it was discovered. Extensive studies over a century have verifi ed its therapeutic eff ects, consistency, and safety with minimal and preventable side effects in medical care. Emerging evidence revealed that ozone also plays important roles in the management and prevention of various skin disorders including infectious skin diseases, skin related allergic diseases, erythema scaly diseases, wound healing and ulcer recovery. Herein, the author now summarizes the recent clinical applications of ozone therapy in dermatology and provide commentary on what we have learned in our practice. Our focuses are the effi cacy and safety of ozone therapies as well as the application prospects of ozone on various skin disorders. In addition, the author discusses the potential mechanisms involved in ozone therapy and the eff orts we should make for.