基于中药质量常数的炙甘草饮片等级评价研究

中药饮片等级是表征饮片质量最明了、最直接的方式,是实现饮片优质优价的依据,是保障行业健康发展的基础。因此,中药饮片等级评价研究备受重视并在行业中迅速兴起。而近年来,中药质量常数评价方法以其具有综合、可量化的特点,在饮片等级研究中渐渐获得了认可和应用。该文基于中药质量常数评价方法建立炙甘草饮片等级标准。从饮片企业收集20批炙甘草饮片,将合格的14批样品分别测定外观性状指标和内在质量指标,计算其中药质量常数,并划分等级。结果表明炙甘草饮片相对质量常数范围0. 70～14. 08,百分质量常数范围4. 95～100. 00。若把炙甘草饮片划分成3等级,则一等炙甘草饮片相对质量常数≥11. 27,或百分质量常数≥80. 03;二等炙甘草饮片相对质量常数<11. 27且≥7. 04,或百分质量常数<80. 03且≥49. 99;三等炙甘草饮片相对质量常数<7. 04,或百分质量常数<49. 99。该研究表明中药质量常数方法能客观地划分炙甘草饮片等级,同时为复杂炮制工艺饮片的等级研究提供了参考。此外,对中药质量常数具有评价饮片质量差异的内涵进行了探讨,便于扩大应用。

Research on grades evaluation of Glycyrrizae Radix et Rhizoma Praeparata Cum Melle based on Chinese medicine quality constant

Grade of Chinese medicine slices is the most clear and most direct way to characterize the quality of Chinese medicine slices,also the basis of realizing " good quality and good prices",and it can guarantee the industry health development. Therefore,grade evaluation of Chinese medicine slices( GECMS) is highly valued and has grown rapidly in the industry. In recent years,due to the comprehensive and measureable features,the Chinese medicine quality constant evaluation method has been gradually recognized and applied.The paper is to establish a method of grades evaluation of Glycyrrizae Radix et Rhizoma Praeparata Cum Melle( GRRPCM) based on the Chinese medicine quality constant. 20 batches of samples were collected from Chinese herbal slices enterprises and 14 batches of qualified samples were selected to determine their external morphological indexes and inner quality indexes,then their Chinese medicine quality constants were calculated and the grades were determined. The results revealed that the relative quality constant of these samples ranged from 0. 70 to 14. 08,with a percentage quality constant from 4. 95 to 100. 00. If these samples were divided into three grades: the relative quality constant shall be ≥11. 27 or percentage quality constant ≥80. 03 for the first grade;the relative quality constant shall be <11. 27 but ≥7. 04,or percentage quality constant <80. 03 and ≥49. 99 for the second grade;while for the third grade,the relative quality constant shall be <7. 04 or the percentage quality constant <49. 99. This research indicates that Chinese quality constant can be used to objectively grade the herbal slices,providing reference for grades standard development of complex processing slices. In addition,the connotation of GECMS that has evaluate the mass discrepancy is discussed for expanding application.