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肌层浸润性膀胱癌保留膀胱的综合治疗策略
引用本文:李博伦,李源.肌层浸润性膀胱癌保留膀胱的综合治疗策略[J].中南大学学报(医学版),2018,43(1):82-89.
作者姓名:李博伦  李源
作者单位:中南大学湘雅医院泌尿外科,长沙 410008
基金项目:国家自然科学基金青年基金(81001137);湖南省自然科学基金(2015JJ3158);湖南省科技厅一般项目(2010sk3102)。
摘    要:膀胱癌是泌尿系常见的恶性肿瘤,其中肌层浸润性膀胱癌的标准治疗方案是膀胱根治性切除术,但该手 术对于患者自身及术后生活均会造成巨大的影响。对此,不少国内外学者指出部分合适的患者可以选择以保留膀胱 的手术为主,同时辅以放射治疗、化学治疗等辅助性治疗的综合治疗方案,术后对患者进行密切的随访,其疗效同 根治性膀胱切除术相近,且手术风险及并发症的发生率也显著低于根治性膀胱切除术,而患者则可以保留有功能的 膀胱。

关 键 词:肌层浸润性膀胱癌  保留膀胱治疗  三联治疗  

Comprehensive therapy of bladder preservation for muscle invasive bladder cancer
LI Bolun,LI Yuan.Comprehensive therapy of bladder preservation for muscle invasive bladder cancer[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),2018,43(1):82-89.
Authors:LI Bolun  LI Yuan
Institution:Department of Urology, Xiangya Hospital, Central South University, Changsha 410008, China
Abstract:Th e bladder cancer is a common malignant tumor in urinary system. Th e standard treatment for muscle invasive bladder cancer is radical cystectomy. Considering the damage to patients and the drastic eff ect on their life caused by the radical cystectomy, many domestic and overseas scholars suggest a comprehensive treatment based on a bladder-keeping surgery with adjuvant therapy including radiotherapy, chemotherapy and frequent follow-up, which showslow operation-related risk and complication rate compared with the radical cystectomy. As a result, patients are able to preserve the function of bladder.
Keywords:muscle invasive bladder cancer  bladder preservation therapy  trimodality treatment  
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