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ERCP术后胰腺炎的预防策略
引用本文:谷保红,李雪梅,胡继科,张凡,鲁娟娟,陈昊.ERCP术后胰腺炎的预防策略[J].中南大学学报(医学版),2019,44(2):209-215.
作者姓名:谷保红  李雪梅  胡继科  张凡  鲁娟娟  陈昊
作者单位:兰州大学第二临床医学院,兰州,730030;兰州大学第二医院肿瘤外科,兰州,730030
基金项目:国家自然科学基金(81470791,81670594);甘肃省基础研究创新群体项目(1606RJIA328);中央高校基本科 研业务费专项资金(lzujbky-2017-79);兰州市人才创新创业项目(2017-RC-62)。
摘    要:经内镜逆行性胰胆管造影术(endoscopic retrograde cholangiopancreatography,ERCP)是胆胰疾病内镜微创诊治 的重要手段,但与其他内镜操作相比,ERCP术后相关的并发症最高。ERCP术后胰腺炎(post-ERCP pancreatitis,PEP) 是其中最常见的并发症,严重时可能危及生命。积极的早期预防可以有效降低PEP的发生率。目前,在临床上有明确 效果的措施包括术前非甾体抗炎药纳肛和预防性胰管支架置入,使用乳酸林格氏液积极的水化也是预防PEP安全有效 的方法。

关 键 词:ERCP术后胰腺炎  危险因素  药物预防  引流  内镜预防

Preventive strategy for post-ERCP pancreatitis
GU Baohong,LI Xuemei,HU Jike,ZHANG Fan,LU Juanjuan,CHEN Hao.Preventive strategy for post-ERCP pancreatitis[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),2019,44(2):209-215.
Authors:GU Baohong  LI Xuemei  HU Jike  ZHANG Fan  LU Juanjuan  CHEN Hao
Institution:1. Second Clinical Medical College, Lanzhou University, Lanzhou 730030; 2. Department of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China
Abstract:Endoscopic retrograde cholangiopancreatography (ERCP) is an irreplaceable measure with minimally invasive diagnosis and treatment of endoscopy for biliary and pancreatic diseases, but the related complications associated with ERCP are the highest among the endoscopic procedures. Post-ERCP pancreatitis (PEP) is one of the most common complications with life-threatening in severe cases. Early active prevention can eff ectively reduce the incidence of post-ERCP pancreatitis. At present, measures including preoperative rectal non-steroidal anti-inflammatory drugs and prophylactic pancreatic stent placement, have definite effective strategy in clinic. Aggressive hydration with lactated Ringer’s solution is also a safe and eff ective way to prevent PEP.
Keywords:post-ERCP pancreatitis  risk factors  drug prevention  drainage  endoscopic prevention  
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