应用异种皮联合延迟微型皮移植术治疗大面积烧伤患者

目的：观察脱细胞猪皮移植术联合延迟微型皮移植术运用于大面积深度烧伤治疗的临床效果。方法：将大面积烧伤患者40例分为治疗组和对照组。治疗组切削痂后行异种皮覆盖，5 d后行延迟微型皮移植术；对照组切削痂后采用传统的异体皮移植术联合微粒皮移植的传统手术方法，观察两组患者的治愈率、微型皮片的成活率、创面封闭时间。结果：两组患者的治愈率相同，均为90%，创面封闭时间差异无统计学意义(P>0.05)，但治疗组患者每1%创面治疗费用较对照组显著降低(P<0.05)，且皮片存活率较对照组增高(P<0.05)。结论：大面积烧伤切削痂后行异种皮联合延迟自体微型皮移植术修复效果理想，为大张异体皮加微粒皮移植提供了新的替代术式。

Application of combination of xenoskin with delayed microskin graft in extensively burned patients

Objective: To observe clinical effects of combination of acellular porcine skin with delayed microskin graft on extensively burned patients. Methods: Forty extensively burned patients were assigned into a treatment group and a control group. In the treatment group, 20 patients were covered with acellular porcine skin after escharectomy, and the delayed microskin grafting was performed 5 days later. In the control group, 20 patients were covered with allograft skin combined with microskin graft after escharectomy. The cure rate, the graft survival rate, wound healing time and cost per 1% wound were observed. Results: The cure rate for the 2 groups was the same (90%), and wound healing time was similar between the two groups (P>0.05). The graft survival rate in the treatment group was higher than that in the control group (P<0.05), and cost per 1% wound in the treatment group was less than that in the control group (P<0.05). Conclusion: The combination of acellular porcine skin with delayed microskin graft is an effective method to treat extensively burned patients, and it provides an ideal substitute for allograft skin combined with microskin graft.