肺癌18F-氟脱氧葡萄糖正电子发射型计算机断层显像检查的卫生经济学

18F-氟脱氧葡萄糖正电子发射型计算机断层显像(18F-fl uorodeoxyglucose positron-emission tomography comparedwith computed tomography，18F-FDG PET-CT，简称PET-CT)用于孤立性肺结节(solitary pulmonary nodule，SPN)及肺癌诊断的敏感性和特异性较常规影像检查显著提高。从卫生经济学角度而言，PET-CT用于恶性肿瘤风险偏中的SPN最具成本效果性，且对于肺癌的术前分期诊断及放射治疗、化学治疗后的随访都具有较好的卫生经济学价值。PET-CT用于肺癌诊疗的卫生经济学研究大多采用的评价方法、效果指标及比较方法分别为成本效果分析、生命年和计算增量成本效果比。病例追踪和随访是早期PET-CT卫生经济学研究的一种手段，而近年来大多数研究所采用的都是模型法。

Health economics analysis for 18F-fluorodeoxyglucose positron-emission tomography compared with computed tomography in lung cancer

Compared with conventional imaging, 18F-fluorodeoxyglucose positron-emission tomographycompared with computed tomography (18F-FDG PET/CT) possesses higher sensitivity andspecificity in the diagnosis of solitary pulmonary nodule (SPN) and lung cancer. From theperspective of health economics, PET/CT is more suitable strategy for diagnose of SPN withintermediate probability of malignancy, and has good health economics value in preoperativestaging diagnosis and follow-up aft er radiotherapy and chemotherapy of lung cancer. Th e evaluationmethod, eff ect index and comparison method used in the health economics research of PET/CTfor lung cancer diagnosis and treatment are cost-eff ect analysis, life year and incremental cost-eff ect ratio, respectively. Case tracking and follow-up was a means of early studies on PET/CT healtheconomics, and in recent years mathematical models are used in most studies.