21 972例口腔黏膜病临床分析

目的：分析湖南省口腔黏膜病的发病情况和分布特点。方法：收集2013年4月至2017年3月就诊于中南大 学湘雅医院口腔内科门诊的所有患者的临床资料，经过筛选、去重、归类后，对疾病病种、性别及年龄分布进行分 析。结果：21 972例口腔黏膜病中，40~49岁女性患者居多，男女比例为1:1.05，按病种分类前9位分别是复发性口腔 溃疡(27.17%)、灼口综合征(15.72%)、口腔黏膜下纤维化(14.75%)、口腔扁平苔藓(10.38%)、口腔白斑(4.21%)、创伤性 溃疡(4.14%)、慢性唇炎(3.47%)、口腔真菌感染(3.26%)、萎缩性舌炎(2.74%)。其中复发性口腔溃疡(28.65%)、灼口综 合征(23.70%)及口腔扁平苔藓(13.31%)是湖南省女性口腔黏膜病前3位病种。口腔黏膜下纤维化是湖南省男性最好发的 口腔黏膜病(28.56%)。结论：复发性口腔溃疡、灼口综合征及口腔扁平苔藓是湖南省女性高发的口腔黏膜病，口腔黏 膜下纤维化是湖南省男性最好发的口腔黏膜病。

Clinical analysis for oral mucosal disease in 21 972 cases

Objective: To analyze the incidence and distribution of oral mucosal diseases in Hunan Province and provide reference for prevention and treatment. Methods: The clinical data for all patients, who were treated in Xiangya Hospital of Central South University from April 2013 to March 2017, were collected. After screening, weighing and classifying, sex and age distribution for the disease was analyzed. Results: Th e female with the age between 40 to 49 were in the majority among 21 972 patients. Th e ratio between men to women was 1:1.05. According to the classifi cation of diseases, the most common diseases were as follows: recurrent aphthous ulcer (27.17%), burning mouth syndrome(15.72%), oral submucous fibrosis (14.75%), oral lichen planus (10.38%), oral leukoplakia (4.21%), traumatic ulceration (4.14%), chronic cheilitis (3.47%), oral fungal infection (3.26%), and atrophic glossitis (2.74%). Recurrent oral ulcer (28.65%), burning mouth syndrome (23.70%) and oral lichen planus (13.31%) were the most common 3 kinds of oral mucosal diseases during females in Hunan. Oral submucous fibrosis was the most common oral mucosal disease among males in Hunan (28.56%). Conclusion: Recurrent oral ulcer, burning mouth syndrome and oral lichen planus are very popular in women in Hunan Province, and oral submucous fibrosis is the most common disease in male in this region. It shows a high trend of incidence in the surrounding provinces.