| 唾液皮质醇与围引产期抑郁的相关性 |
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| 引用本文： | 张小红,盛江明,黄迟,孛尔之巾·阿拉坦嘎茹迪,刘梦祥,彭慧婷,秦春香. 唾液皮质醇与围引产期抑郁的相关性[J]. 中南大学学报(医学版), 2019, 44(9): 1023-1029. DOI: 10.11817/j.issn.1672-7347.2019.190407 |
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| 作者姓名： | 张小红 盛江明 黄迟 孛尔之巾·阿拉坦嘎茹迪 刘梦祥 彭慧婷 秦春香 |
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| 作者单位： | 中南大学 1. 湘雅三医院急诊科,长沙 410013;2. 湘雅二医院老年病科,长沙 410011;3. 湘雅护理学院,长沙 410013;4. 湘雅三医院产科,长沙 410013 |
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| 基金项目： | 国家自然科学基金(71704191);湖南省自然科学基金(2018JJ6055);湖南省科技创新计划(2017TP1004)。 |
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| 摘 要： | 目的：探索胎儿畸形引产女性引产前唾液皮质醇水平的相关参数与围引产期抑郁的关系。方法：比较胎儿畸形女性引产前后抑郁组与非抑郁组之间唾液皮质醇水平的差异,应用logistics回归分析唾液皮质醇与围引产期抑郁发生的相关关系。结果：胎儿畸形引产女性抑郁组唾液皮质醇觉醒反应低于非抑郁组,引产前唾液皮质醇觉醒反应与引产前(OR=0.063,95% CI：0.005~0.754)和引产后3个月(OR=0.002,95% CI：0.000~0.061)抑郁的发生呈负相关。结论：唾液皮质醇觉醒反应越高,围引产期抑郁发生率越低,提示胎儿畸形引产女性引产前唾液皮质醇觉醒反应对引产后抑郁的发生有预测作用。
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| 关 键 词： | 胎儿畸形 抑郁 唾液皮质醇 皮质醇觉醒反应 |
Salivary cortisol level and peri-abortion depression |
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| ZHANG Xiaohong,SHENG Jiangming,HUANG Chi,BORJIGEN·Altangarvdi,LIU Mengxiang,PENG Huiting,QIN Chunxiang. Salivary cortisol level and peri-abortion depression[J]. Journal of Central South University. Medical sciences, 2019, 44(9): 1023-1029. DOI: 10.11817/j.issn.1672-7347.2019.190407 |
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| Authors: | ZHANG Xiaohong SHENG Jiangming HUANG Chi BORJIGEN·Altangarvdi LIU Mengxiang PENG Huiting QIN Chunxiang |
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| Affiliation: | 1. Department of Emergency, Th ird Xiangya Hospital, Central South University, Changsha 410013; 2. Departmentof Geriatric, Second Xiangya Hospital, Central South University, Changsha 410011; 3. Xiangya Nursing School, Central South University, Changsha 410013; 4. Department of Obstetrics, Th ird Xiangya Hospital, Central South University, Changsha 410013, China |
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| Abstract: | Objective: To study the salivary cortisol level, and to analyze the correlation between salivarycortisol and peri-abortion depression in the women suffering termination of pregnancy for fetalanomaly.Methods: Comparing the diff erence in salivary cortisol level between the women with and withoutdepression when they underwent termination of pregnancy for fetal anomaly in a prospectivecohort study. Analyzing the correlation between salivary cortisol and peri-abortion depressionthrough logistics regression analysis.Results: The salivary cortisol awakening response was lower in women with depression thanwomen without depression. Based on the logistics regression analysis, the salivary cortisolawakening response showed a negative correlation with pre-abortion (OR=0.063, 95% CI 0.005 to0.754) and post-abortion (OR=0.002, 95% CI 0.000 to 0.061) depression.Conclusion: Cortisol awakening response possesses a negative correlation with peri-abortiondepression, and it is a predictive factor for post-abortion depression. |
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| Keywords: | fetal anomaly depression salivary cortisol cortisol awakening response |
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