音乐干预对晚期肿瘤患者化疗期间生活质量的影响

目的探讨晚期肿瘤患者化疗期间实施音乐疗法干预，对减轻化疗毒副作用，提高患者生活质量的效果。方法根据患者一天的心理规律特点，设计一套系统音乐，包括：晨间护理“A”曲，镇痛“B”，进餐“C”曲，入睡“D”曲。将符合条件的患者100例随机分为音乐组（50例）和对照组（50例），音乐组患者每次化疗过程或间歇期予音乐治疗干预，对照组不实施音乐治疗干预。用症状评定量表（SANS）评定干预前后两组患者症状评分，并观察比较两组患者每次化疗过程副作用及化疗后血象的变化。结果音乐组患者音乐治疗干预后，心情愉快，镇静安宁，每次化疗后毒副反应程度轻，对照组患者副作用明显，两组患者化疗后副作用及化疗后血象变化比较差异有统计学意义（P〈0．05）；音乐组治疗前后SANS评分比较差异有统计学意义（P〈0．05），对照组治疗前后SANS评分比较差异无统计学意义（P〉0．05）；治疗后两组SANS评分比较差异有统计学意义（P〈0．05）。结论在患者化疗期间实施音乐干预可减轻化疗副作用，稳定患者血象，减轻患者心理恐惧，直接提高患者生存质量。

Effect of music intervention on quality of life in advanced cancer patients during chemotherapy

Objective To explore the effect of music therapy on reducing chemotherapy toxicity, improving the quality of life of the patients with advanced cancer patients during chemotherapy.Methods According to psychological law characteristics of patients, we design a music system, including: morning nursing "A" song, analgesia "B", dine "C" song, sleep "D" song. 100 advanced cancer patients from the affiliated hospital of guangdong medical college, between June 2009 and June 2010, were enrolled in this study. They were randomly divided into two groups according to numerical table. The control group (50 patients) received routine nursing, while the experimental group (50 patients) received music therapy intervention during each chemotherapy process or break. The effects were evaluated from two aspects: the side effects of chemotherapy and the changes of blood-routine after chemotherapy.Results The experimental group feel cheerfulness, tranquil at every time after chemotherapy and the degree of adverse reaction is light, than the control group, and there were significant differences between them (P<0.05). The SANS scores in experimental group were different before and after intervention(P<0.05), while the SANS scores in control group did not reach statistical difference (P>.05), and the SANS scores were significantly different between the two groups(P<0.05).Conclusions Music intervention during each chemotherapy process can reduce side effects of chemotherapy, balance patients' blood-route, ease patients' psychological fear, and directly improve survival quality.