肝硬化患者睡眠状况与焦虑抑郁发生情况的调查

目的调查分析肝炎后肝硬化患者睡眠状况与焦虑、抑郁发生情况，为采取针对性干预措施提供依据。方法采用睡眠状况自评量表（SRSS）、焦虑自评量表（SAS）、抑郁自评量表（SDS）对72例住院的肝硬化患者进行问卷调查。结果肝硬化患者与全国常模SRSS评分中，睡眠质量、睡眠不稳因子、失眠后反应得分及总分比较差异有统计学意义（P〈0．01或P〈0．05）；不同病程患者失眠情况的比较差异有统计学意义（P〈0．01）；不同性别患者SDS、SAS评定结果的比较差异均有统计学意义（P〈0．05）。70．8％的患者存在不同程度的失眠，高于全国常模45．6％，差异有统计学意义（x2=18．366，P〈0．01）。不同性别肝硬化患者中，有69．44％的患者存在焦虑，女性高于男性；有62．50％的患者存在抑郁，男性高于女性，差异均有统计学意义（P〈0．05）。结论肝炎后肝硬化患者失眠、焦虑、抑郁的存在具有普遍性、特殊性，应引起医护人员的足够重视。

Investigation of sleeping status, anxiety and depression in patients with liver cirrhosis

Objective To investigate sleeping status, anxiety and depression in patients with liver cirrhosis so as to provide basis for intervention measures.Methods Self-rating Scale of Sleep (SRSS), Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) were used to investigate 72 inpatients with liver cirrhosis.Results Scores of factors of sleeping quality, sleeping unsteady and response after insomnia among the patients had significant difference compared with the national norm (P<0.01 or P<0.05). Significant differences were found among patients with different degrees of insomnia (P<0.01). There were significant differences in terms of SDS and SAS between males and females(P＜0.05). 70.8% of the patients had insomnia in various degrees, higher than the national norm 45.6%. The difference was statistically significant (χ2=18.366,P<0.01). Among liver cirrhosis patients of different sex, 69.44% of them had anxiety, and the rate was higher in females than in males, while 62.50% of them had depression, and the rate was higher in males than in females(P<0.05).Conclusions Insomnia, anxiety and depression are commonly and particularly found in patients with liver cirrhosis, and should draw the medical staff's attention.