| 西洋参茎叶皂甙对兔主动脉条收缩反应的影响 |
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| 引用本文： | 关利新,衣欣,冯芹喜,杨履艳.西洋参茎叶皂甙对兔主动脉条收缩反应的影响[J].中国中药杂志,1996,21(7):431-434. |
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| 作者姓名： | 关利新 衣欣 冯芹喜 杨履艳 |
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| 作者单位： | 牡丹江医学院 |
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| 摘 要： | 西洋参茎叶皂甙１．２ｍｇ／ｍｌ对ＮＥ，ＫＣｌ，ＣａＣｌ２收缩兔主动脉条的量效曲线呈非竞争性拮抗，并能明显抑制ＮＥ引起的主动脉条依细胞内及细胞外Ｃａ２＋收缩。其作用性质与维拉帕米相似。
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| 关 键 词： | 西洋参茎叶皂甙，钙通道阻滞剂，去甲肾上腺素，氯化钾，主动脉 |
| 收稿时间： | 1995/2/28 0:00:00 |
Effects of Saponins from Stems and Leaves of Panax quinquefolium L.on Contraction of Rabbit Aortic Strips |
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| Guan Lixin;Yi Xin;Feng Qinxi; Yang Luyan.Effects of Saponins from Stems and Leaves of Panax quinquefolium L.on Contraction of Rabbit Aortic Strips[J].China Journal of Chinese Materia Medica,1996,21(7):431-434. |
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| Authors: | Guan Lixin;Yi Xin;Feng Qinxi; Yang Luyan |
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| Institution: | MudanJiang Medical College 1577011 |
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| Abstract: | It has been found out that the saponins from stems and leaves of Panax,quinque folium(PQS)cannon-competitively antagonize the dose-response curves of norepinephrine(NE),potassium chloride and calcium chlo-ride on the isolated aortic strips of rabbits, and obviously inhibit intracellular and extracellular Ca2+-dependent con-traction of the aortic strips induced by NE. These effects of PQS are similar to verapamil. |
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| Keywords: | PQS calcium channel blocker norepinephrine potassium chloride aorta |
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