新疆叶城县维吾尔族、汉族2型糖尿病合并冠心病患者血脂水平的对比性研究

目的探讨新疆叶城县维吾尔族(维族)、汉族2型糖尿病合并冠心病与血脂异常的关系及临床意义。方法回顾性分析2009年1月至2010年12月在新疆叶城县解放军第18医院住院的维族、汉族2型糖尿病患者348例,并发冠心病233例,测定血脂水平并进行比较。结果 2型糖尿病合并冠心病患者血甘油三酯(TG)、胆固醇(TC)水平明显高于非合并冠心病患者,其中维族患者TG2.87±0.52 vs 2.03±0.43]、TC5.74±0.63 vs 4.91±0.54]水平,汉族患者TG2.11±0.34 vs 1.82±0.36]、TC5.52±0.43 vs 4.62±0.45]水平高于各自的非冠心病组(P<0.05)。维族患者以高甘油三酯(TG)血症为主(男性39.57%vs 31.48%,女性31.09%vs 25.00%,P<0.05),汉族患者以高胆固醇(TC)血症为主(男性12.96%vs 7.19%,女性13.89%vs 6.72%,P<0.05)。结论 TG、TC升高是2型糖尿病并发冠心病的重要危险因素,在控制血糖的同时应控制血脂异常,以期减少糖尿病动脉硬化的发生。受检患者血脂异常,脂质代谢紊乱类型存在民族差异。

Blood lipid levels in Uygur and Han patients with type 2 diabetes mellitus accom-panying coronary heart disease in Yecheng County, Xinjiang Uygur Autonomous Region: A comparative study

Objective To compare the blood lipid levels in Uygur and Han patients with type 2 diabetes mellitus(DM) accompanying coronary heart disease(Yecheng County,Xinjiang Autonomous Region,China) and their clinical significance.Methods Blood lipid levels in 348 patients with type 2 DM accompanying coronary heart disease admitted to No.18 Hospital of PLA from January 2009 to December 2010 were retrospectively analyzed.Results The triglyceride(TG) and total cholesterol(TC) levels were higher in patients with type 2 DM accompanying coronary heart disease than in those not accompanying coronary heart disease.The TG and TC levels were higher in Uygur and Han patients with type 2 DM than in those not accompanying coronary heart disease(TG: 2.87±0.52 vs 2.03±0.43 and TC:5.74±0.63 vs 4.91±0.54 in Uygur;TG: 2.11±0.34 vs 1.82±0.36 and TC: 5.52±0.43 vs 4.62±0.45 In Han,P<0.05).The incidence of hypercholesterolemia was higher in Uygur patients than in Han patients(12.96% vs 7.19% in male patients and 13.89% vs 6.72% in female patients,P<0.05).Conclusion High TG and TC level is the important risk factor for type 2 DM accompanying coronary heart disease.Controlling blood sugar and lipid level can reduce the incidence of diabetic arteriosclerosis.The blood lipid levels and lipid metabolic disorder types are different in different nationalities.